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 Volume 68, Number 19, May 08, 2007
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NEUROLOGY 2007;68:1618-1621
© 2007 American Academy of Neurology

Tracheostomy can fatally exacerbate sleep-disordered breathing in multiple system atrophy

K. Jin, MD, S. Okabe, MD, PhD, K. Chida, MD, PhD, N. Abe, MD, PhD, T. Kimpara, MD, PhD, A. Ohnuma, MD, PhD, H. Nomura, MD, PhD, Y. Itoyama, MD, PhD and H. Onodera, MD, PhD

From the Department of Neurology (K.J., K.C., N.A.), Iwate National Hospital, Sendai Sleep Clinic (S.O.), Department of Neurology (T.K., A.O., H.N.), Kohnan Hospital, Department of Neurology (Y.I.), Tohoku University School of Medicine, and Department of Neurology (H.O.), Nishitaga National Hospital, Japan.

Address correspondence and reprint requests to Dr. K. Jin, Department of Neurology, Iwate National Hospital, 48 Dorotayama-shita, Yamanome, Ichinoseki, Iwate 021-0056, Japan jink{at}em.neurol.med.tohoku.ac.jp

Tracheostomy has been employed to release the airway obstruction at the glottic level and to prevent sudden death in patients with multiple system atrophy (MSA). However, sudden death is possible even after tracheostomy. Nocturnal polysomnography showed that the apnea–hypopnea index became higher after tracheostomy, and all tracheostomized patients had frequent central sleep apneas.

Supplemental data at www.neurology.org

Supported by grants-in-aid for Scientific Research (15659206) from the Ministry of Education, Science, and Culture.

Disclosure: The authors report no conflicts of interest.

Received February 10, 2006. Accepted in final form December 28, 2006.




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Correspondence:

Read all Correspondence

Tracheostomy can fatally exacerbate sleep-disordered breathing in multiple system atrophy
Takayoshi Shimohata, et al.
Neurology Online, 22 Aug 2007 [Full text]
Tracheostomy can fatally exacerbate sleep-disordered breathing in multiple system atrophy
Michael H. Silber
Neurology Online, 22 Aug 2007 [Full text]
Reply from the authors
Kazutaka Jin, et al.
Neurology Online, 22 Aug 2007 [Full text]