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Pathologic gambling in patients with restless legs syndrome treated with dopaminergic agonists

From the Mayo Clinic Sleep Disorders Center (M.T.-P., J.G.P., B.F.B., J.W.S., M.H.S.), Department of Neurology (M.T.-P., B.F.B., M.H.S.), and Division of Pulmonary and Critical Care Medicine (M.T.-P., J.G.P., J.W.S.), Mayo Clinic College of Medicine, Rochester, MN.

Address correspondence and reprint requests to Dr. M. Tippmann-Peikert, Mayo Clinic Sleep Disorders Center, Eisenberg Bldg. 8 G, 200 First Street SW, Rochester, MN 55905; e-mail: tippmannpeikert.maja{at}mayo.edu

Pathologic gambling is an impulse control disorder previously reported to complicate dopamine agonist therapy in patients with Parkinson disease. It has not been described in association with dopamine agonist therapy of other conditions. We report three patients treated in our sleep disorders center who developed pathologic gambling while receiving treatment with dopamine agonists for restless legs syndrome.

Disclosure: The authors report no conflicts of interest.

Received May 23, 2006. Accepted in final form October 17, 2006.

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