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Long-term outcome of bilateral pallidal deep brain stimulation for primary cervical dystonia

From the Movement Disorders Center (S.W.H., Y.-Y.W.P., P.P., J.M.M., A.E.L., E.M.), Division of Neurology, Toronto Western Hospital, University of Toronto, UHN, Toronto, Ontario, Canada; Department of Neurology (S.W.H.), Medical College of Wisconsin, Milwaukee, WI; Division of Neurosurgery (C.H., A.M.L.), Toronto Western Hospital, University of Toronto, UHN, Toronto, Ontario, Canada; Department of Physiology (J.O.D., W.D.H.), University of Toronto, Toronto, Ontario, Canada.

Address correspondence and reprint requests to Dr. Elena Moro, Movement Disorders Centre, Toronto Western Hospital, 399 Bathurst Street, McL-7, Toronto, Ontario, Canada M5T 2S8; e-mail: elena.moro{at}uhn.on.ca

Ten patients with severe cervical dystonia (CD) unresponsive to medical treatment underwent bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) and were followed for 31.9 ± 20.9 months. At last follow-up, the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) severity score improved by 54.8%, the TWSTRS disability score improved by 59.1%, and the TWSTRS pain score improved by 50.4%. Bilateral GPi DBS is an effective long-term therapy in patients with CD.

Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the February 6 issue to find the title link for this article.

Disclosures: Dr. Lozano has received honoraria from Medtronic for consulting service. Drs. Hung, Piboolnurak, Lang, Miyasaki, Dostrovsky, and Hutchison and Ms. Poon have nothing to disclose. Dr. Moro has received honoraria from Medtronic for lecturing at meetings and for consulting service.

Received July 13, 2006. Accepted in final form October 9, 2006.

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