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Sural nerve T-cell receptor Vß gene utilization in chronic inflammatory demyelinating polyneuropathy and vasculitic neuropathy

W.M.J. Bosboom, MD, PhD;, L.H. Van den Berg, MD, PhD;, I. Mollee;, L.D. Sasker;, J. Jansen, PhD;, J.H.J. Wokke, MD, PhD; and T. Logtenberg, PhD

From the Department of Neurology of the Rudolf Magnus Institute for Neurosciences (Drs. Bosboom, Van den Berg, and Wokke, I. Mollee, L.D. Sasker, and J. Jansen); and the Department of Immunology (T. Logtenberg), University Medical Center Utrecht, the Netherlands.



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Figure 1. Consecutive transverse sections of the sural nerve of Patient 3 with (A) anti-CD3-staining and (B) anti-Vß17-staining. Bar = 50 µm.

 


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Figure 2. Vß T-cell receptor utilization in sural nerve and peripheral blood of patients and controls (PCR). Pat = patient; CIDP = chronic inflammatory demyelinating polyneuropathy; Vasc. = vasculitic neuropathy; CIAP = chronic idiopathic axonal polyneuropathy; Normal = autopsy control; H = healthy control.

 





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