Figure 2. Amplitude distribution of quantal excitatory postsynaptic currents (qEPSC) before, during, and after application of the Miller Fisher syndrome (MFS) immunoglobulin G (IgG). Ordinates: numbers of observations per bin. Abscissae: amplitude of qEPSC at a constant depolarizing current (-0.4µA), bin width 200 pA. (A) Control solution; quantal content m = 0.7. (B) MFS-IgG of Patient 11; quantal content m = 0.2. (C) Wash-out (control solution); quantal content m = 0.5. All data were recorded from the same nerve terminal. The number of records evaluated for each distribution were 1,500 to 3,000, depending on quantal content. The solid line marks the gaussian distribution of single quanta.
