Data Supplement

Three tables.

Files in this Data Supplement:

• E1 - Table (E)T-1. Means (+SD) for neuropsychological variables at baseline (Baseline), end of 8-weeks’ dose escalation (Titration), and at end of maintenance phase following 20 weeks’ treatment (Maintenance) for each treatment group. Asterisks denote variables for which lower values correspond to better performance; Table (E)T-2. Statistical results for changes from baseline to the end of the titration period (baseline-titration): ANCOVAs based on change from baseline scores; p values for indicated treatment comparisons; and 95% confidence intervals for all pairwise comparisons; Table (E)T-3. Statistical results for changes from baseline to end of the maintenance period (baseline-maintenance): ANCOVAs based on change from baseline scores; p values for treatment comparisons; and 95% confidence intervals for all pairwise comparisons; Word document.