Data Supplement

Three tables; one Word document.

Files in this Data Supplement:

• E1 - Lesion number and volume analysis (Table (E) T-1); Multiple regression with T2 volume change and T1 hypointense lesion volume change as the dependent variables, MS type as the fixed factor and age as covariate (Table (E) T-2); Correlations: Baseline lesion volumes and ventricular volume change (year 1 - baseline) (Table (E) T-3); Word document.