Teaching NeuroImages: Reversible bilateral thalamic lesions in vein of Galen thrombosis
Rou-Chen Jee, MD and
Sheng-Huang Lin, MD, MSc
From the Department of Neurology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
Address correspondence and reprint requests to Dr. Sheng-Huang Lin, Department of Neurology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan, No. 707, Sec. 3, Chung-Yang Rd., Hualien City, Hualien County 970, Taiwan, Republic of China shlin355{at}gmail.com
A 51-year-old woman was admitted with 2 days of progressivedrowsiness and bradyphrenia. On examination, she had blood pressureof 125/75 mm Hg and a pulse of 68 beats/minute. She arousedto verbal stimuli, and her answers were correct but slow. Therewas no focal weakness or numbness, and reflexes were normal.Brain MRI revealed lesions in bilateral thalami and right caudatenucleus (figure, A) and vein of Galen thrombosis (figure, B).There was no evidence of dehydration, coagulopathy, autoimmunedysfunction, or infection. She recovered completely on heparin.Follow-up brain images were normal (figure, C and D). Earlydetection and treatment of deep cerebral venous thrombosis lowersthe risk of permanent neurologic deficits.1,2
T2-weighted MRI (A) revealed high-signal lesions in bilateral thalami and right caudate nucleus. Magnetic resonance venography (B) showed thrombus formation in vein of Galen (arrow). After treatment, the lesions of bilateral thalami and right caudate nucleus disappeared (C), and the vein of Galen was patent (D).
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