Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
QUICK SEARCH:   [advanced]


     

Published online before print April 20, 2005, doi:10.1212/01.WNL.0000162031.03390.BA)
This Article
Right arrow Full Text (Rapid PDF)
Right arrow Polish Data Supplement
Right arrow All Versions of this Article:
01.WNL.0000162031.03390.BAv1
64/10/1768    most recent
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Pellock, J. M.
Right arrow Articles by Shinnar, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Pellock, J. M.
Right arrow Articles by Shinnar, S.
Received June 28, 2004
Accepted January 27, 2005

Respiratory adverse events associated with diazepam rectal gel

John M. Pellock MD* and Shlomo Shinnar MD, PhD

From the Departments of Neurology, Pediatrics, Pharmacy, and Pharmaceutics (Dr. Pellock), Virginia Commonwealth University, Medical College of Virginia, Richmond; and Departments of Neurology, Pediatrics, and the Comprehensive Epilepsy Management Center (Dr. Shinnar), Montefiore Medical Center and the Albert Einstein College of Medicine, Bronx, NY.


* To whom correspondence should be addressed. E-mail: jpellock{at}hsc.vcu.edu.

Abstract-- The authors reviewed respiratory adverse events and deaths spontaneously reported to Xcel Pharmaceuticals associated with diazepam rectal gel. Over 2 million doses have been prescribed. The authors identified nine respiratory adverse events and three deaths. The respiratory events associated with prolonged seizures had a good outcome. The deaths occurred in the context of a prolonged seizure and respiratory depression was not the main symptom. When used as recommended, diazepam rectal gel has a low rate of serious morbidity or mortality.




This article has been cited by other articles:


Home page
 PediatricsHome page
Steering Committee on Quality Improvement and Mana
Febrile Seizures: Clinical Practice Guideline for the Long-term Management of the Child With Simple Febrile Seizures
Pediatrics, June 1, 2008; 121(6): 1281 - 1286.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
Copyright © 2005 by AAN Enterprises, Inc.