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Published online before print January 25, 2006, doi:10.1212/01.wnl.0000200777.96896.3d)
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Received June 8, 2005
Accepted December 7, 2005

Cerebrovascular reactivity and vasospasm after subarachnoid hemorrhage

J. A. Frontera MD, T. Rundek MD, J. M. Schmidt PhD, J. Claassen MD, A. Parra MD, K. E. Wartenberg MD, R. E. Temes MD, S. A. Mayer MD, J. P. Mohr MD, and R. S. Marshall MD*

From the Department of Neurology, Division of Stroke and Neurocritical Care, Columbia University College of Physicians and Surgeons, New York, NY.


* To whom correspondence should be addressed. E-mail: rsm2{at}columbia.edu.

Abstract--The authors performed serial transcranial Doppler (TCD) and carbon dioxide reactivity (CO2R) testing in 20 aneurysmal subarachnoid hemorrhage patients to determine whether impaired cerebrovascular reactivity was associated with symptomatic vasospasm. Symptomatic vasospasm occurred in 9 of 14 patients with abnormal CO2R and in none of 6 patients with preserved reactivity (p = 0.011). Abnormal CO2R preceded the onset of vasospasm in 7 of 9 patients. Abnormal standard TCD testing was not associated with vasospasm.




This article has been cited by other articles:


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G. K.C. Wong, S. C.P. Ng, W. W.S. Poon, J. A. Frontera, and R. S. Marshall
Cerebrovascular reactivity and vasospasm after subarachnoid hemorrhage: A pilot study
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A. A. Rabinstein
The blood and the vessel: Prediction of cerebral vasospasm after subarachnoid hemorrhage
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Correspondence:

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Cerebrovascular reactivity and vasospasm after subarachnoid hemorrhage
George KC Wong, et al.
Neurology Online, 8 Mar 2006 [Full text]
Reply from the authors
Jennifer A. Frontera, et al.
Neurology Online, 8 Mar 2006 [Full text]

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