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Published online before print November 29, 2006, doi:10.1212/01.wnl.0000246601.70918.06)
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 Volume 67, Number 11, December 12, 2006
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Received January 27, 2006
Accepted June 28, 2006

Intracerebral hemorrhages in CADASIL

Jay Chol Choi MD*, Sa-Yoon Kang MD, Ji-Hoon Kang MD, PhD, and Ji-Kang Park MD

From the Department of Neurology and Radiology (J.-K.P.), Cheju National University Hospital (J.C.C., S.-Y.K., J.-H.K.), Jeju, Korea.


* To whom correspondence should be addressed. E-mail: iguazzu{at}hanmail.net.

Abstract--Intracerebral hemorrhage (ICH) has been described only sporadically for patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). However, cerebral microbleeds (CMBs) were found in 31% to 69% of the patients with CADASIL, and this predicted an increased risk of ICH. In this study, the authors found that 25% of the symptomatic patients with CADASIL had ICHs, and their development was closely related to the number of CMBs.






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