| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH |
|
|
|
|||||||
|
|||||||||
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
From the Center for Clinical Pharmacology (F.H.V., J.N.d.H.), University Hospital Gasthuisberg (K.U. Leuven); and Division of Clinical Pharmacology (L.M.V.B.), Heymans Institute of Pharmacology, Ghent University, Belgium.
* To whom correspondence should be addressed. E-mail: jan.dehoon{at}uz.kuleuven.be.
Abstract Objective: Migraine is associated with cardiovascular disorders but the underlying mechanisms are unknown. Arterial structure and function are important determinants of cardiovascular morbidity and mortality. The aim of the present study was to assess arterial properties in patients with migraine of recent onset. Methods: In a cross-sectional study, structural and functional arterial properties were assessed using ultrasound and applanation tonometry in 50 patients with a history of migraine >1 and <6 years during a headache-free interval and 50 age- and gender-matched subjects without a history of migraine. Results: Brachial artery diameter (4.82 ± 0.93 mm vs 5.39 ± 0.89 mm, p = 0.01) and compliance (0.30 ± 0.17 mm2/kPa vs 0.37 ± 0.19 mm2/kPa, p = 0.02) were decreased in migraine patients compared with controls. Femoral artery compliance was decreased in migraine patients (1.19 ± 0.55 mm2/kPa vs 1.42 ± 0.59 mm2/kPa, p = 0.04). Carotid arterial wall properties were similar between groups. Aortic augmentation index was increased in migraine patients (4 ± 10% vs -1 ± 10%, adjusted p = 0.04). Flow-mediated vasodilation of the brachial artery (normalized to peak shear rate) was decreased in patients with migraine (29 ± 15 vs 37 ± 15 10-3%. sec, p = 0.006). Conclusion: Functional arterial properties are altered in patients with migraine of recent onset.
This article has been cited by other articles:
|
|
 |
|
  M. Schurks, P. M Rist, M. E Bigal, J. E Buring, R. B Lipton, and T. Kurth Migraine and cardiovascular disease: systematic review and meta-analysis BMJ, October 27, 2009; 339(oct27_1): b3914 - b3914. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. E. Tietjen, N. A. Herial, L. White, C. Utley, J. M. Kosmyna, and S. A. Khuder Migraine and Biomarkers of Endothelial Activation in Young Women Stroke, September 1, 2009; 40(9): 2977 - 2982. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H.-C. Diener and C. A. Beck Migraine and risk of cardiovascular disease in women: Learning about relative and absolute risk Neurology, August 25, 2009; 73(8): 576 - 577. [Full Text] [PDF]
|
|
|
|
|
|
R. Napoli, V. Guardasole, E. Zarra, M. Matarazzo, C. D'Anna, F. Sacca, F. Affuso, A. Cittadini, P. B. Carrieri, and L. Sacca Vascular smooth muscle cell dysfunction in patients with migraine Neurology, June 16, 2009; 72(24): 2111 - 2114. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. D Bushnell, M. Jamison, and A. H James Migraines during pregnancy linked to stroke and vascular diseases: US population based case-control study BMJ, March 10, 2009; 338(mar10_2): b664 - b664. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Schwaiger, S. Kiechl, H. Stockner, M. Knoflach, P. Werner, G. Rungger, A. Gasperi, and J. Willeit Burden of atherosclerosis and risk of venous thromboembolism in patients with migraine Neurology, September 16, 2008; 71(12): 937 - 943. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Kurth, M. Schurks, G. Logroscino, J M. Gaziano, and J. E Buring Migraine, vascular risk, and cardiovascular events in women: prospective cohort study BMJ, August 7, 2008; 337(aug07_1): a636 - a636. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. B. Gorelick and J. V. Bowler Advances in Vascular Cognitive Impairment 2007 Stroke, February 1, 2008; 39(2): 279 - 282. [Full Text] [PDF]
|
|
|
|
|
|
M. A. Moskowitz and T. Kurth Blood Vessels, Migraine, and Stroke Stroke, December 1, 2007; 38(12): 3117 - 3118. [Full Text] [PDF]
|
|
|
|
|
|
S. R. Brenner, D. S. Summers, and J. N. de Hoon ALTERED ARTERIAL FUNCTION IN MIGRAINE OF RECENT ONSET Neurology, November 20, 2007; 69(21): 2028 - 2029. [Full Text] [PDF]
|
|
|
|
 |
|
 T. Kurth, J. M. Gaziano, N. R. Cook, V. Bubes, G. Logroscino, H.-C. Diener, and J. E. Buring Migraine and Heart Rate Variability Reply Arch Intern Med, November 12, 2007; 167(20): 2264 - 2265. [Full Text] [PDF]
|
|
|
|
|
|
G. E. Tietjen Migraine as a systemic disorder Neurology, May 8, 2007; 68(19): 1555 - 1556. [Full Text] [PDF]
|
|
Read all Correspondence
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH |
