HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Correspondence: Submit a response Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Ovbiagele, B. Articles by Saver, J. L. Search for Related Content PubMed PubMed Citation Articles by Ovbiagele, B. Articles by Saver, J. L.

Are elevated admission calcium levels associated with better outcomes after ischemic stroke?

From the Stroke Center and Department of Neurology (B.O., D.S.L., S.S., N.S., D.K., T.R., J.L.S.) and Department of Emergency Medicine (S.S.), UCLA Medical Center, Los Angeles, CA.

Address correspondence and reprint requests to Dr. Bruce Ovbiagele, Stroke Center and Department of Neurology, University of California at Los Angeles, 710 Westwood Plaza, Los Angeles, CA 90095; e-mail: ovibes{at}mednet.ucla.edu

Calcium (Ca²⁺) and magnesium (Mg²⁺) influence the molecular pathways of ischemic neuronal death. The authors evaluated the impact of admission serum Ca²⁺ and Mg²⁺ levels, on incident stroke severity and discharge functional outcome. After adjusting for covariates, higher admission Ca²⁺ was significantly associated with lesser stroke severity and better discharge functional outcome. Admission Mg²⁺ was not an independent clinical outcome prognosticator.

This study was supported in part by NIH-National Institute of Neurologic Disorders and Stroke Awards P50 NS044378.

Disclosure: The authors report no conflicts of interest.

Received November 17, 2005. Accepted in final form March 17, 2006.

This article has been cited by other articles:

				B. Ovbiagele, S. Starkman, P. Teal, P. Lyden, M. Kaste, S. M. Davis, W. Hacke, M. Fierus, J. L. Saver, and on behalf of the VISTA Investigators Serum Calcium as Prognosticator in Ischemic Stroke Stroke, August 1, 2008; 39(8): 2231 - 2236. [Abstract] [Full Text] [PDF]

				B. H. Buck, D. S. Liebeskind, J. L. Saver, O. Y. Bang, S. Starkman, L. K. Ali, D. Kim, J. P. Villablanca, N. Salamon, S. W. Yun, et al. Association of Higher Serum Calcium Levels With Smaller Infarct Volumes in Acute Ischemic Stroke Arch Neurol, September 1, 2007; 64(9): 1287 - 1291. [Abstract] [Full Text] [PDF]