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Published online before print November 29, 2006, doi:10.1212/01.wnl.0000246601.70918.06)
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Volume 67, Number 11, December 12, 2006
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01.wnl.0000246601.70918.06v1
67/11/2042    most recent
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NEUROLOGY 2006;67:2042-2044
© 2006 American Academy of Neurology


Brief Communications

Intracerebral hemorrhages in CADASIL

Jay Chol Choi, MD, Sa-Yoon Kang, MD, Ji-Hoon Kang, MD, PhD and Ji-Kang Park, MD

From the Department of Neurology and Radiology (J.-K.P.), Cheju National University Hospital (J.C.C., S.-Y.K., J.-H.K.), Jeju, Korea.

Address correspondence and reprint requests to Dr. Jay Chol Choi, Department of Neurology, Cheju National University Hospital, 154 Samdo 2-dong, Jeju-si, Jeju-do, 690-716, Korea; e-mail: iguazzu{at}hanmail.net

Intracerebral hemorrhage (ICH) has been described only sporadically for patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). However, cerebral microbleeds (CMBs) were found in 31% to 69% of the patients with CADASIL, and this predicted an increased risk of ICH. In this study, the authors found that 25% of the symptomatic patients with CADASIL had ICHs, and their development was closely related to the number of CMBs.


This article was previously published in electronic format as an Expedited E-Pub at www.neurology.org.

Supported by a grant from the Cheju National University Hospital Research Fund (2004).

Disclosure: The authors report no conflicts of interest.

Received January 27, 2006. Accepted in final form June 28, 2006.







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