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Volume 68, Number 9, February 27, 2007
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NEUROLOGY 2007;68:694-697
© 2007 American Academy of Neurology

Comparison of CT perfusion and angiography and MRI in selecting stroke patients for acute treatment

M. Wintermark, MD, R. Meuli, MD, P. Browaeys, MD, M. Reichhart, MD, J. Bogousslavsky, MD, P. Schnyder, MD and P. Michel, MD

From the Department of Radiology (M.W.), University of California, San Francisco; and Departments of Radiology (R.M., P.B., P.S.) and Neurology (M.R., P.M.), University Hospital (CHUV), Lausanne, and Department of Neurology (J.B.), Genolier Swiss Medical Network Valmont Clinic, Glion-sur-Montreux, Switzerland.

Address correspondence and reprint requests to Dr. M. Wintermark, Neuroradiology Section, Department of Radiology, University of California, San Francisco (UCSF), 505 Parnassus Ave., Box 0628, San Francisco, CA 94143-0628; e-mail: Max.Wintermark{at}radiology.ucsf.edu

Forty-two stroke patients successively underwent perfusion CT (PCT)/CT angiography (CTA) and MRI examinations within 3 to 9 hours following symptom onset; 14 would have been suitable candidates for reperfusion treatment based on MRI findings. Correlation between PCT/CTA and MRI was excellent for infarct size, cortical involvement, and internal cerebral artery occlusion and substantial for penumbra/infarct ratio. Relying on MRI or PCT/CTA would have led to the same treatment decisions in all cases but one.


Disclosure: Max Wintermark is a consultant for Paion GmbH and Forest Laboratories. The other authors report no conflicts of interest.

Received June 16, 2006. Accepted in final form November 7, 2006.




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