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ARTICLES: K. M. Rose, A. P. Carson, C. P. Sanford, P. E. Stang, C. A. Brown, A. R. Folsom, and M. Szklo Migraine and other headaches: Associations with Rose angina and coronary heart disease Neurology 2004; 63: 2233-2239 [Abstract] [Full text] [PDF]

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Migraine and other headaches: Associations with Rose angina and coronary heart disease

Abraham R. Totah   (1 February 2005)

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Kathryn Rose   (1 February 2005)

Migraine and other headaches: Associations with Rose angina and coronary heart disease 1 February 2005
Abraham R. Totah, 1399 Hamlet Avenue Clearwater, FL 33756 Send Correspondence to journal: Re: Migraine and other headaches: Associations with Rose angina and coronary heart disease atotah{at}hotmail.com Abraham R. Totah	Rose et al present an intriguing article. It would have been helpful if a definition of "Rose angina" would have been provided. I erroneously assumed that Rose angina was synonomous with vasospastic angina given the association of vasospastic phenomenon with migraine. A Medline search of the phrase "Rose angina" produced three hundred and twenty one citations, whereas a search of the word angina alone produced over forty five thousand citations. A term that is used only 0.7% of the time by specialists who are non-neurologists deserves a definition in a neurology journal.
Reply to Totah 1 February 2005
Kathryn Rose, Cardiovascular Disease Program, Department of Epidemiology University of North Carolina at Chapel Hill, 137 E. Franklin St., Suite 306, Chapel Hill, NC 27514 Send Correspondence to journal: Re: Reply to Totah Kathryn_Rose{at}unc.edu Kathryn Rose	The London School of Hygiene Chest Pain Questionnaire (Rose Angina Questionnaire) [1] is widely used in epidemiologic studies as a standardized research tool to screen for exertional angina. It is not a diagnostic test. It consists of a series of questions about chest pain with Rose angina being defined based on a participant’s responses to questions about the location of pain as well as its onset/cessation in response to physical activity (e.g. walking up a hill). In the literature, Rose angina is associated with coronary heart disease [2,3] although some studies suggest that it has higher specificity in men than women. [2,4,5] The Rose angina questionnaire does not measure vasospastic angina. References 1. Rose GA. Chest pain questionnaire. Milbank Memorial Fund Quarterly 1965; 43:32-39. 2. Sorlie PD, Cooper L, Schreiner PJ, Rosamond W, Szklo M. Repeatability and validity of the Rose questionnaire for angina pectoris in the Atherolsclerosis Risk in Communities Study. J Clin Epidemiol 1996; 49:719-725. 3. LaCroix AZ, Guralnik JM, Curb JD, Wallace RB, Ostfeld AM, Hennekens CH. Chest pain and coronary heart disease mortality among older men and women in three communities. Circulation. 1990;81(2):437-446. 4. Bass EB, Follansbee WP, Orchard TJ. Comparison of a supplemented Rose questionnaire to exercise thallium testing in men and women. J Clin Epidemiol 1989; 42:385-393. 5. Garber CE, Carleton RA, Heller GV. Comparison of “Rose questionnaire angina” to exercise tahllium scintigraphy: different findings in males and females. J Clin Epidemiol 1992; 45:715-720.