In their article, Evers et al state, "Oral zolmitriptan 2.5mg offered significant pain relief
and pain freedom vs. placebo. This study shows that an oral triptan can
be efficacious in the treatment of migraine in this age group." [1] In my opinion this statement should be, "Oral
zolmitriptan 2.5 mg offered no significant increase in pain relief and
pain freedom than ibuprofen."
In my practice, I see children with migraines having
been on triptans but never having had a trial of ibuprofen or
acetaminophen/aspirin/caffeine, another inexpensive, safe, and
efficacious medication. [2] How can we justify starting with a
medication that costs $15 per pill when there are other alternatives that
are cheap, safe nonprescription and efficacious? It is our responsibility to hold down health care costs.
References
1. Evers S, Rahmann A, Kraemer C, et al. Treatment of childhood migraine attacks with oral zolmitriptan and ibuprofen. Neurology 2006; 67: 497-499
2. Goldstein J, Silberstein, SD. et al: Acetaminophen,
aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial. Headache 2005;45:973-982.
Disclosure: The author reports no conflicts of interest.
The author had the opportunity to respond but declined.