INTRODUCTION:

Robert H. Dworkin and John T. Farrar

Research design issues in pain clinical trials
Neurology 2005 65: S1-S2. [Full Text]  

ARTICLES:

Delbert R. Black and Christine N. Sang

Advances and limitations in the evaluation of analgesic combination therapy
Neurology 2005 65: S3-S6. [Abstract] [Full Text] [Figures Only]  

Robert H. Dworkin, Jennifer Katz, and Michael J. Gitlin

Placebo response in clinical trials of depression and its implications for research on chronic neuropathic pain
Neurology 2005 65: S7-S19. [Abstract] [Full Text]  

Jennifer A. Haythornthwaite

Clinical trials studying pharmacotherapy and psychological treatments alone and together
Neurology 2005 65: S20-S31. [Abstract] [Full Text]  

Nathaniel Katz

Methodological issues in clinical trials of opioids for chronic pain
Neurology 2005 65: S32-S49. [Abstract] [Full Text]  

R. B. Lipton, M. E. Bigal, and W. F. Stewart

Clinical trials of acute treatments for migraine including multiple attack studies of pain, disability, and health-related quality of life
Neurology 2005 65: S50-S58. [Abstract] [Full Text] [Figures Only]  

Elna M. Nagasako and Donna A. Kalauokalani

Ethical aspects of placebo groups in pain trials: Lessons from psychiatry
Neurology 2005 65: S59-S65. [Abstract] [Full Text]  

Michael C. Rowbotham

Mechanisms of neuropathic pain and their implications for the design of clinical trials
Neurology 2005 65: S66-S73. [Abstract] [Full Text]  

Mitchell B. Max

Afterword: Five steps to increase the payoff of chronic pain trials
Neurology 2005 65: S74-S77. [Full Text]  

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