Obesity does not induce abnormal CSF pressure in subjects with normal cerebral MR venography
Abstract
Obesity has been shown to increase lumbar CSF pressure in healthy subjects. The authors studied lumbar CSF opening pressure in 18 obese, 33 overweight, and 49 nonoverweight subjects with normal MRI and MR venography (MRV) of the brain. No subject had a CSF pressure above 200 mm H2O. Obesity does not cause abnormal CSF pressure in subjects with normal MRV. Individuals with a CSF pressure higher than 200 mm H2O should undergo MRV to exclude cerebral venous thrombosis.
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References
1.
Fishmann RA, ed. Cerebrospinal fluid in diseases of the nervous system. 2nd ed. Philadephia: Saunders, 1992.
2.
Gilland O, Tourtellotte WW, O’Tauma L, et al. Normal cerebrospinal fluid pressure. J Neurosurg . 1974; 40: 587–593.
3.
Corbett JJ, Mehta MP. Cerebrospinal fluid pressure in normal obese subjects and patients with pseudotumor cerebri. Neurology . 1983; 33: 1386–1388.
4.
Hannerz J, Greitz D, Ericson K. Is there a relationship between obesity and intracranial hypertension? Int J Obes Relat Metab Disord . 1995; 19: 240–244.
5.
Quattrone A, Gambardella A, Carbone AM, et al. A hypofibrinolytic state in overweight patients with cerebral venous thrombosis and isolated intracranial hypertension. J Neurol . 1999; 246: 1086–1089.
6.
Quattrone A, Bono F, Oliveri RL, et al. Cerebral venous thrombosis and isolated intracranial hypertension without papilledema in CDH. Neurology . 2001; 57: 31–36.
7.
Biousse V, Ameri A, Bousser M-G. Isolated intracranial hypertension as the only sign of cerebral venous thrombosis. Neurology . 1999; 53: 1537–1542.
8.
Sugerman HJ, Felton WL, Salvant JB, et al. Effects of surgically induced weight loss on idiopathic intracranial hypertension in morbid obesity. Neurology . 1995; 45: 1655–1659.
9.
Bloomfield GL, Ridings PC, Blocher CR, et al. A proposed relationship between increased intra-abdominal, intrathoracic, and intracranial pressure. Crit Care Med . 1997; 25: 496–503.
10.
King JO, Mitchell PJ, Thomson KR, et al. Manometry combined with cervical puncture in idiopathic intracranial hypertension. Neurology . 2002; 58: 26–30.
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Publication History
Received: March 25, 2002
Accepted: August 9, 2002
Published online: November 26, 2002
Published in print: November 26, 2002
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