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December 22, 2003

Efficacy of the Atkins diet as therapy for intractable epilepsy

December 23, 2003 issue
61 (12) 1789-1791

Abstract

The ketogenic diet is effective for treating seizures in children with epilepsy. The Atkins diet can also induce a ketotic state, but has fewer protein and caloric restrictions, and has been used safely by millions of people worldwide for weight reduction. Six patients, aged 7 to 52 years, were started on the Atkins diet for the treatment of intractable focal and multifocal epilepsy. Five patients maintained moderate to large ketosis for periods of 6 weeks to 24 months; three patients had seizure reduction and were able to reduce antiepileptic medications. This provides preliminary evidence that the Atkins diet may have a role as therapy for patients with medically resistant epilepsy.

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Information & Authors

Information

Published In

Neurology®
Volume 61Number 12December 23, 2003
Pages: 1789-1791
PubMed: 14694049

Publication History

Received: July 11, 2003
Accepted: September 8, 2003
Published online: December 22, 2003
Published in print: December 23, 2003

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Authors

Affiliations & Disclosures

Eric H. Kossoff, MD
From the Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, MD.
Gregory L. Krauss, MD
From the Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, MD.
Jane R. McGrogan, RD
From the Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, MD.
John M. Freeman, MD
From the Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, MD.

Notes

Address correspondence and reprint requests to Dr. Eric H. Kossoff, Jefferson 128, The Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD 21287-1000; e-mail: [email protected]

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  2. The effects of ketogenic and chitosan-based diets on submandibular salivary gland in rat model: a comparative histological study, BMC Oral Health, 24, 1, (2024).https://doi.org/10.1186/s12903-024-03885-8
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  9. A Review of Ketogenic Dietary Therapies for Epilepsy and Neurological Diseases: A Proposal to Implement an Adapted Model to Include Healthy Mediterranean Products, Foods, 12, 9, (1743), (2023).https://doi.org/10.3390/foods12091743
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