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September 13, 2004

The prevalence of pain in multiple sclerosis
A multicenter cross-sectional study

September 14, 2004 issue
63 (5) 919-921

Abstract

In a multicenter cross-sectional study, the authors assessed pain in patients with multiple sclerosis (MS) using a symptom-oriented approach. Out of 2,077 questionnaires, we used 1,672 for data analysis. Pain and frequencies included trigeminal neuralgia 2%, Lhermitte’s sign 9%, dysesthetic pain 18.1%, back pain 16.4%, and painful tonic spasms 11%. Comparison between different groups showed significant differences for age, Expanded Disability Status Scale, disease duration, and disease course, but not for sex. This study underlines the relevance of pain in the clinical history of MS.

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Information & Authors

Information

Published In

Neurology®
Volume 63Number 5September 14, 2004
Pages: 919-921
PubMed: 15365151

Publication History

Received: December 12, 2003
Accepted: May 8, 2004
Published online: September 13, 2004
Published in print: September 14, 2004

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Authors

Affiliations & Disclosures

C. Solaro, MD
From the Department of Neurology (Dr. Solaro), “P.A. Micone” Hospital, Genova; Departments of Neurosciences, Ophthalmology, and Genetics (Drs. Brichetto and Mancardi) and Centre of Excellence for Biomedical Research (Dr. Mancardi), University of Genova; Department of Neurology and Psychiatry (Dr. Amato), University of Firenze; Department of Neurosciences (Dr. Cocco), University of Cagliari; Department of Neurology (Drs. Colombo and Martinelli), S. Raffaele Hospital, Milan; Neurolesi Centre (Dr. D’Aleo), AUSL 5 Messina; Department of Neurosciences (Dr. Gasperini), S. Camillo Forlanini Hospital, Rome; MS Centre (Dr. Ghezzi), S. Antonio Abate Hospital, Gallarate; “C. Besta” Neurological Institute (Dr. Milanese), Milan; Department of Neurosciences (Dr. Patti), MS Centre University of Catania; Department of Neurological Sciences (Dr. Trojano), Bari; and Department of Neurology (Dr. Verdun), Torino, Italy.
G. Brichetto, MD
From the Department of Neurology (Dr. Solaro), “P.A. Micone” Hospital, Genova; Departments of Neurosciences, Ophthalmology, and Genetics (Drs. Brichetto and Mancardi) and Centre of Excellence for Biomedical Research (Dr. Mancardi), University of Genova; Department of Neurology and Psychiatry (Dr. Amato), University of Firenze; Department of Neurosciences (Dr. Cocco), University of Cagliari; Department of Neurology (Drs. Colombo and Martinelli), S. Raffaele Hospital, Milan; Neurolesi Centre (Dr. D’Aleo), AUSL 5 Messina; Department of Neurosciences (Dr. Gasperini), S. Camillo Forlanini Hospital, Rome; MS Centre (Dr. Ghezzi), S. Antonio Abate Hospital, Gallarate; “C. Besta” Neurological Institute (Dr. Milanese), Milan; Department of Neurosciences (Dr. Patti), MS Centre University of Catania; Department of Neurological Sciences (Dr. Trojano), Bari; and Department of Neurology (Dr. Verdun), Torino, Italy.
M. P. Amato, MD
From the Department of Neurology (Dr. Solaro), “P.A. Micone” Hospital, Genova; Departments of Neurosciences, Ophthalmology, and Genetics (Drs. Brichetto and Mancardi) and Centre of Excellence for Biomedical Research (Dr. Mancardi), University of Genova; Department of Neurology and Psychiatry (Dr. Amato), University of Firenze; Department of Neurosciences (Dr. Cocco), University of Cagliari; Department of Neurology (Drs. Colombo and Martinelli), S. Raffaele Hospital, Milan; Neurolesi Centre (Dr. D’Aleo), AUSL 5 Messina; Department of Neurosciences (Dr. Gasperini), S. Camillo Forlanini Hospital, Rome; MS Centre (Dr. Ghezzi), S. Antonio Abate Hospital, Gallarate; “C. Besta” Neurological Institute (Dr. Milanese), Milan; Department of Neurosciences (Dr. Patti), MS Centre University of Catania; Department of Neurological Sciences (Dr. Trojano), Bari; and Department of Neurology (Dr. Verdun), Torino, Italy.
E. Cocco, MD
From the Department of Neurology (Dr. Solaro), “P.A. Micone” Hospital, Genova; Departments of Neurosciences, Ophthalmology, and Genetics (Drs. Brichetto and Mancardi) and Centre of Excellence for Biomedical Research (Dr. Mancardi), University of Genova; Department of Neurology and Psychiatry (Dr. Amato), University of Firenze; Department of Neurosciences (Dr. Cocco), University of Cagliari; Department of Neurology (Drs. Colombo and Martinelli), S. Raffaele Hospital, Milan; Neurolesi Centre (Dr. D’Aleo), AUSL 5 Messina; Department of Neurosciences (Dr. Gasperini), S. Camillo Forlanini Hospital, Rome; MS Centre (Dr. Ghezzi), S. Antonio Abate Hospital, Gallarate; “C. Besta” Neurological Institute (Dr. Milanese), Milan; Department of Neurosciences (Dr. Patti), MS Centre University of Catania; Department of Neurological Sciences (Dr. Trojano), Bari; and Department of Neurology (Dr. Verdun), Torino, Italy.
B. Colombo, MD
From the Department of Neurology (Dr. Solaro), “P.A. Micone” Hospital, Genova; Departments of Neurosciences, Ophthalmology, and Genetics (Drs. Brichetto and Mancardi) and Centre of Excellence for Biomedical Research (Dr. Mancardi), University of Genova; Department of Neurology and Psychiatry (Dr. Amato), University of Firenze; Department of Neurosciences (Dr. Cocco), University of Cagliari; Department of Neurology (Drs. Colombo and Martinelli), S. Raffaele Hospital, Milan; Neurolesi Centre (Dr. D’Aleo), AUSL 5 Messina; Department of Neurosciences (Dr. Gasperini), S. Camillo Forlanini Hospital, Rome; MS Centre (Dr. Ghezzi), S. Antonio Abate Hospital, Gallarate; “C. Besta” Neurological Institute (Dr. Milanese), Milan; Department of Neurosciences (Dr. Patti), MS Centre University of Catania; Department of Neurological Sciences (Dr. Trojano), Bari; and Department of Neurology (Dr. Verdun), Torino, Italy.
G. D’Aleo, MD
From the Department of Neurology (Dr. Solaro), “P.A. Micone” Hospital, Genova; Departments of Neurosciences, Ophthalmology, and Genetics (Drs. Brichetto and Mancardi) and Centre of Excellence for Biomedical Research (Dr. Mancardi), University of Genova; Department of Neurology and Psychiatry (Dr. Amato), University of Firenze; Department of Neurosciences (Dr. Cocco), University of Cagliari; Department of Neurology (Drs. Colombo and Martinelli), S. Raffaele Hospital, Milan; Neurolesi Centre (Dr. D’Aleo), AUSL 5 Messina; Department of Neurosciences (Dr. Gasperini), S. Camillo Forlanini Hospital, Rome; MS Centre (Dr. Ghezzi), S. Antonio Abate Hospital, Gallarate; “C. Besta” Neurological Institute (Dr. Milanese), Milan; Department of Neurosciences (Dr. Patti), MS Centre University of Catania; Department of Neurological Sciences (Dr. Trojano), Bari; and Department of Neurology (Dr. Verdun), Torino, Italy.
C. Gasperini, MD
From the Department of Neurology (Dr. Solaro), “P.A. Micone” Hospital, Genova; Departments of Neurosciences, Ophthalmology, and Genetics (Drs. Brichetto and Mancardi) and Centre of Excellence for Biomedical Research (Dr. Mancardi), University of Genova; Department of Neurology and Psychiatry (Dr. Amato), University of Firenze; Department of Neurosciences (Dr. Cocco), University of Cagliari; Department of Neurology (Drs. Colombo and Martinelli), S. Raffaele Hospital, Milan; Neurolesi Centre (Dr. D’Aleo), AUSL 5 Messina; Department of Neurosciences (Dr. Gasperini), S. Camillo Forlanini Hospital, Rome; MS Centre (Dr. Ghezzi), S. Antonio Abate Hospital, Gallarate; “C. Besta” Neurological Institute (Dr. Milanese), Milan; Department of Neurosciences (Dr. Patti), MS Centre University of Catania; Department of Neurological Sciences (Dr. Trojano), Bari; and Department of Neurology (Dr. Verdun), Torino, Italy.
A. Ghezzi, MD
From the Department of Neurology (Dr. Solaro), “P.A. Micone” Hospital, Genova; Departments of Neurosciences, Ophthalmology, and Genetics (Drs. Brichetto and Mancardi) and Centre of Excellence for Biomedical Research (Dr. Mancardi), University of Genova; Department of Neurology and Psychiatry (Dr. Amato), University of Firenze; Department of Neurosciences (Dr. Cocco), University of Cagliari; Department of Neurology (Drs. Colombo and Martinelli), S. Raffaele Hospital, Milan; Neurolesi Centre (Dr. D’Aleo), AUSL 5 Messina; Department of Neurosciences (Dr. Gasperini), S. Camillo Forlanini Hospital, Rome; MS Centre (Dr. Ghezzi), S. Antonio Abate Hospital, Gallarate; “C. Besta” Neurological Institute (Dr. Milanese), Milan; Department of Neurosciences (Dr. Patti), MS Centre University of Catania; Department of Neurological Sciences (Dr. Trojano), Bari; and Department of Neurology (Dr. Verdun), Torino, Italy.
V. Martinelli, MD
From the Department of Neurology (Dr. Solaro), “P.A. Micone” Hospital, Genova; Departments of Neurosciences, Ophthalmology, and Genetics (Drs. Brichetto and Mancardi) and Centre of Excellence for Biomedical Research (Dr. Mancardi), University of Genova; Department of Neurology and Psychiatry (Dr. Amato), University of Firenze; Department of Neurosciences (Dr. Cocco), University of Cagliari; Department of Neurology (Drs. Colombo and Martinelli), S. Raffaele Hospital, Milan; Neurolesi Centre (Dr. D’Aleo), AUSL 5 Messina; Department of Neurosciences (Dr. Gasperini), S. Camillo Forlanini Hospital, Rome; MS Centre (Dr. Ghezzi), S. Antonio Abate Hospital, Gallarate; “C. Besta” Neurological Institute (Dr. Milanese), Milan; Department of Neurosciences (Dr. Patti), MS Centre University of Catania; Department of Neurological Sciences (Dr. Trojano), Bari; and Department of Neurology (Dr. Verdun), Torino, Italy.
C. Milanese, MD
From the Department of Neurology (Dr. Solaro), “P.A. Micone” Hospital, Genova; Departments of Neurosciences, Ophthalmology, and Genetics (Drs. Brichetto and Mancardi) and Centre of Excellence for Biomedical Research (Dr. Mancardi), University of Genova; Department of Neurology and Psychiatry (Dr. Amato), University of Firenze; Department of Neurosciences (Dr. Cocco), University of Cagliari; Department of Neurology (Drs. Colombo and Martinelli), S. Raffaele Hospital, Milan; Neurolesi Centre (Dr. D’Aleo), AUSL 5 Messina; Department of Neurosciences (Dr. Gasperini), S. Camillo Forlanini Hospital, Rome; MS Centre (Dr. Ghezzi), S. Antonio Abate Hospital, Gallarate; “C. Besta” Neurological Institute (Dr. Milanese), Milan; Department of Neurosciences (Dr. Patti), MS Centre University of Catania; Department of Neurological Sciences (Dr. Trojano), Bari; and Department of Neurology (Dr. Verdun), Torino, Italy.
F. Patti, MD
From the Department of Neurology (Dr. Solaro), “P.A. Micone” Hospital, Genova; Departments of Neurosciences, Ophthalmology, and Genetics (Drs. Brichetto and Mancardi) and Centre of Excellence for Biomedical Research (Dr. Mancardi), University of Genova; Department of Neurology and Psychiatry (Dr. Amato), University of Firenze; Department of Neurosciences (Dr. Cocco), University of Cagliari; Department of Neurology (Drs. Colombo and Martinelli), S. Raffaele Hospital, Milan; Neurolesi Centre (Dr. D’Aleo), AUSL 5 Messina; Department of Neurosciences (Dr. Gasperini), S. Camillo Forlanini Hospital, Rome; MS Centre (Dr. Ghezzi), S. Antonio Abate Hospital, Gallarate; “C. Besta” Neurological Institute (Dr. Milanese), Milan; Department of Neurosciences (Dr. Patti), MS Centre University of Catania; Department of Neurological Sciences (Dr. Trojano), Bari; and Department of Neurology (Dr. Verdun), Torino, Italy.
M. Trojano, MD
From the Department of Neurology (Dr. Solaro), “P.A. Micone” Hospital, Genova; Departments of Neurosciences, Ophthalmology, and Genetics (Drs. Brichetto and Mancardi) and Centre of Excellence for Biomedical Research (Dr. Mancardi), University of Genova; Department of Neurology and Psychiatry (Dr. Amato), University of Firenze; Department of Neurosciences (Dr. Cocco), University of Cagliari; Department of Neurology (Drs. Colombo and Martinelli), S. Raffaele Hospital, Milan; Neurolesi Centre (Dr. D’Aleo), AUSL 5 Messina; Department of Neurosciences (Dr. Gasperini), S. Camillo Forlanini Hospital, Rome; MS Centre (Dr. Ghezzi), S. Antonio Abate Hospital, Gallarate; “C. Besta” Neurological Institute (Dr. Milanese), Milan; Department of Neurosciences (Dr. Patti), MS Centre University of Catania; Department of Neurological Sciences (Dr. Trojano), Bari; and Department of Neurology (Dr. Verdun), Torino, Italy.
E. Verdun, MD
From the Department of Neurology (Dr. Solaro), “P.A. Micone” Hospital, Genova; Departments of Neurosciences, Ophthalmology, and Genetics (Drs. Brichetto and Mancardi) and Centre of Excellence for Biomedical Research (Dr. Mancardi), University of Genova; Department of Neurology and Psychiatry (Dr. Amato), University of Firenze; Department of Neurosciences (Dr. Cocco), University of Cagliari; Department of Neurology (Drs. Colombo and Martinelli), S. Raffaele Hospital, Milan; Neurolesi Centre (Dr. D’Aleo), AUSL 5 Messina; Department of Neurosciences (Dr. Gasperini), S. Camillo Forlanini Hospital, Rome; MS Centre (Dr. Ghezzi), S. Antonio Abate Hospital, Gallarate; “C. Besta” Neurological Institute (Dr. Milanese), Milan; Department of Neurosciences (Dr. Patti), MS Centre University of Catania; Department of Neurological Sciences (Dr. Trojano), Bari; and Department of Neurology (Dr. Verdun), Torino, Italy.
G. L. Mancardi, MD
From the Department of Neurology (Dr. Solaro), “P.A. Micone” Hospital, Genova; Departments of Neurosciences, Ophthalmology, and Genetics (Drs. Brichetto and Mancardi) and Centre of Excellence for Biomedical Research (Dr. Mancardi), University of Genova; Department of Neurology and Psychiatry (Dr. Amato), University of Firenze; Department of Neurosciences (Dr. Cocco), University of Cagliari; Department of Neurology (Drs. Colombo and Martinelli), S. Raffaele Hospital, Milan; Neurolesi Centre (Dr. D’Aleo), AUSL 5 Messina; Department of Neurosciences (Dr. Gasperini), S. Camillo Forlanini Hospital, Rome; MS Centre (Dr. Ghezzi), S. Antonio Abate Hospital, Gallarate; “C. Besta” Neurological Institute (Dr. Milanese), Milan; Department of Neurosciences (Dr. Patti), MS Centre University of Catania; Department of Neurological Sciences (Dr. Trojano), Bari; and Department of Neurology (Dr. Verdun), Torino, Italy.
the PaIMS Study Group
From the Department of Neurology (Dr. Solaro), “P.A. Micone” Hospital, Genova; Departments of Neurosciences, Ophthalmology, and Genetics (Drs. Brichetto and Mancardi) and Centre of Excellence for Biomedical Research (Dr. Mancardi), University of Genova; Department of Neurology and Psychiatry (Dr. Amato), University of Firenze; Department of Neurosciences (Dr. Cocco), University of Cagliari; Department of Neurology (Drs. Colombo and Martinelli), S. Raffaele Hospital, Milan; Neurolesi Centre (Dr. D’Aleo), AUSL 5 Messina; Department of Neurosciences (Dr. Gasperini), S. Camillo Forlanini Hospital, Rome; MS Centre (Dr. Ghezzi), S. Antonio Abate Hospital, Gallarate; “C. Besta” Neurological Institute (Dr. Milanese), Milan; Department of Neurosciences (Dr. Patti), MS Centre University of Catania; Department of Neurological Sciences (Dr. Trojano), Bari; and Department of Neurology (Dr. Verdun), Torino, Italy.

Notes

Address correspondence and reprint requests to Dr. Claudio Solaro, Department of Neurology, “P.A. Micone” Hospital, Genova, Italy; e-mail: [email protected]

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