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October 10, 2005

Transverse sinus stenoses persist after normalization of the CSF pressure in IIH

October 11, 2005 issue
65 (7) 1090-1093

Abstract

Background: Bilateral transverse sinus (TS) stenosis has been found in more than 90% of patients with idiopathic intracranial hypertension (IIH).
Objective: To evaluate whether TS stenosis changed after normalization of CSF pressure in patients with IIH during medical treatment.
Methods: Fourteen consecutive patients with IIH with bilateral TS stenosis on cerebral MR venography (MRV) during the medical treatment were studied. Patients were followed for over a 6-year period. During the follow-up, patients underwent repeated lumbar punctures (LPs) and cerebral MRV. MRV was always performed before each LP.
Results: TS stenosis persisted in all the patients during the follow-up. In 9 of 14 (64%) patients with IIH, CSF pressure normalized during medical treatment.
Conclusions: Transverse sinus (TS) stenoses, as revealed by MR venography, persist in patients with idiopathic intracranial hypertension after normalization of CSF pressure, suggesting the lack of a direct relationship between the caliber of TS and CSF pressure.

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Published In

Neurology®
Volume 65Number 7October 11, 2005
Pages: 1090-1093
PubMed: 16217064

Publication History

Published online: October 10, 2005
Published in print: October 11, 2005

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Authors

Affiliations & Disclosures

F. Bono, MD
From the Institutes of Neurology (Drs. Bono, Giliberto, Mastrandrea, Cristiano, and Quattrone) and Neurosurgery (Dr. Lavano), University Magna Græcia, Catanzaro, and Institute of Neurological Sciences (Drs. Fera, Quattrone), National Research Council, Piano Lago di Mangone, Cosenza, Italy.
C. Giliberto, MD
From the Institutes of Neurology (Drs. Bono, Giliberto, Mastrandrea, Cristiano, and Quattrone) and Neurosurgery (Dr. Lavano), University Magna Græcia, Catanzaro, and Institute of Neurological Sciences (Drs. Fera, Quattrone), National Research Council, Piano Lago di Mangone, Cosenza, Italy.
C. Mastrandrea, MD
From the Institutes of Neurology (Drs. Bono, Giliberto, Mastrandrea, Cristiano, and Quattrone) and Neurosurgery (Dr. Lavano), University Magna Græcia, Catanzaro, and Institute of Neurological Sciences (Drs. Fera, Quattrone), National Research Council, Piano Lago di Mangone, Cosenza, Italy.
D. Cristiano, MD
From the Institutes of Neurology (Drs. Bono, Giliberto, Mastrandrea, Cristiano, and Quattrone) and Neurosurgery (Dr. Lavano), University Magna Græcia, Catanzaro, and Institute of Neurological Sciences (Drs. Fera, Quattrone), National Research Council, Piano Lago di Mangone, Cosenza, Italy.
A. Lavano, MD
From the Institutes of Neurology (Drs. Bono, Giliberto, Mastrandrea, Cristiano, and Quattrone) and Neurosurgery (Dr. Lavano), University Magna Græcia, Catanzaro, and Institute of Neurological Sciences (Drs. Fera, Quattrone), National Research Council, Piano Lago di Mangone, Cosenza, Italy.
F. Fera, MD
From the Institutes of Neurology (Drs. Bono, Giliberto, Mastrandrea, Cristiano, and Quattrone) and Neurosurgery (Dr. Lavano), University Magna Græcia, Catanzaro, and Institute of Neurological Sciences (Drs. Fera, Quattrone), National Research Council, Piano Lago di Mangone, Cosenza, Italy.
A. Quattrone, MD
From the Institutes of Neurology (Drs. Bono, Giliberto, Mastrandrea, Cristiano, and Quattrone) and Neurosurgery (Dr. Lavano), University Magna Græcia, Catanzaro, and Institute of Neurological Sciences (Drs. Fera, Quattrone), National Research Council, Piano Lago di Mangone, Cosenza, Italy.

Notes

Address correspondence and reprint requests to Prof. A. Quattrone, Clinica Neurologica, Policlinico MaterDomini, Via T. Campanella, 88100 Catanzaro, Italy; e-mail: [email protected]

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