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March 13, 2006

Somatosensory cortical atrophy after spinal cord injury: A voxel-based morphometry study

M. T. Jurkiewicz, PhD, A. P. Crawley, PhD, M. C. Verrier, MHSc, M. G. Fehlings, MD, PhD, and D. J. Mikulis, MDAuthors Info & Affiliations
March 14, 2006 issue
66 (5) 762-764
https://doi.org/10.1212/01.wnl.0000201276.28141.40
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Abstract

The authors used voxel-based morphometry to compare sensorimotor cortical gray and white matter volume on structural MR images of a group of 17 individuals with cervical spinal cord injury (SCI) and a group of 17 healthy subjects. SCI subjects had reduced gray matter volume bilaterally in primary somatosensory cortex (p < 0.001). These findings suggest that the somatosensory cortex of the human brain atrophies after SCI.

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Information & Authors

Information

Published In

Neurology®
Volume 66 • Number 5 • March 14, 2006
Pages: 762-764
PubMed: 16534122

Copyright

© 2006.

Publication History

Published online: March 13, 2006
Published in print: March 14, 2006

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Authors

Affiliations & Disclosures

M. T. Jurkiewicz, PhD
From the Department of Physiology (M.T.J., M.C.V.), University of Toronto, Toronto; Department of Medical Imaging (M.T.J., A.P.C., D.J.M.), Toronto Western Hospital of the University Health Network, Toronto; Departments of Physical Therapy and Rehabilitation Science (M.C.V.), University of Toronto, Toronto; Toronto Rehabilitation Institute (M.C.V.), Toronto; Department of Surgery (M.G.F.), Toronto Western Hospital of the University Health Network, Toronto, Ontario, Canada.
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A. P. Crawley, PhD
From the Department of Physiology (M.T.J., M.C.V.), University of Toronto, Toronto; Department of Medical Imaging (M.T.J., A.P.C., D.J.M.), Toronto Western Hospital of the University Health Network, Toronto; Departments of Physical Therapy and Rehabilitation Science (M.C.V.), University of Toronto, Toronto; Toronto Rehabilitation Institute (M.C.V.), Toronto; Department of Surgery (M.G.F.), Toronto Western Hospital of the University Health Network, Toronto, Ontario, Canada.
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M. C. Verrier, MHSc
From the Department of Physiology (M.T.J., M.C.V.), University of Toronto, Toronto; Department of Medical Imaging (M.T.J., A.P.C., D.J.M.), Toronto Western Hospital of the University Health Network, Toronto; Departments of Physical Therapy and Rehabilitation Science (M.C.V.), University of Toronto, Toronto; Toronto Rehabilitation Institute (M.C.V.), Toronto; Department of Surgery (M.G.F.), Toronto Western Hospital of the University Health Network, Toronto, Ontario, Canada.
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M. G. Fehlings, MD, PhD
From the Department of Physiology (M.T.J., M.C.V.), University of Toronto, Toronto; Department of Medical Imaging (M.T.J., A.P.C., D.J.M.), Toronto Western Hospital of the University Health Network, Toronto; Departments of Physical Therapy and Rehabilitation Science (M.C.V.), University of Toronto, Toronto; Toronto Rehabilitation Institute (M.C.V.), Toronto; Department of Surgery (M.G.F.), Toronto Western Hospital of the University Health Network, Toronto, Ontario, Canada.
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D. J. Mikulis, MD
From the Department of Physiology (M.T.J., M.C.V.), University of Toronto, Toronto; Department of Medical Imaging (M.T.J., A.P.C., D.J.M.), Toronto Western Hospital of the University Health Network, Toronto; Departments of Physical Therapy and Rehabilitation Science (M.C.V.), University of Toronto, Toronto; Toronto Rehabilitation Institute (M.C.V.), Toronto; Department of Surgery (M.G.F.), Toronto Western Hospital of the University Health Network, Toronto, Ontario, Canada.
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Notes

Address correspondence and reprint requests to Dr. David J. Mikulis, Department of Medical Imaging, Toronto Western Hospital, McLaughlin 3MC-431, 399 Bathurst Street, Toronto, Ontario, Canada M5T 2S8; e-mail: [email protected]

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