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March 26, 2007

Cross-cultural variation in mental health at end of life in patients with ALS

March 27, 2007 issue
68 (13) 1058-1061

Abstract

Objective: To examine mental health at the end of life among patients with ALS in three countries: Israel, Germany, and the United States.
Methods: Patients met criteria for definite or probable ALS and had forced vital capacity (FVC) <60% of predicted. Patients completed nonsomatic items from the Beck Depression Inventory and visual analogue scale ratings.
Results: The three sites contributed a total of 92 patients; 60 died during follow-up. Patients at the three sites did not differ significantly in sociodemographic features or ALS Functional Rating Scale–Revised summary disability score; sites differed in use of nasal ventilation but not percutaneous esophageal gastrostomy (PEG) tube placement. In analyses that adjusted for disability and use of nasal ventilation, patients at the three sites differed in reports of pessimism and suffering; American patients reported the least distress and Israeli patients the most. In analyses limited to people who died, similar patterns emerged, with wish to live greatest in Americans and least among Israelis. These models adjusted for disability and days until death.
Conclusions: Cultural factors may affect mental health at the end of life in patients with ALS.

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Information & Authors

Information

Published In

Neurology®
Volume 68Number 13March 27, 2007
Pages: 1058-1061
PubMed: 17389312

Publication History

Published online: March 26, 2007
Published in print: March 27, 2007

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Authors

Affiliations & Disclosures

S. M. Albert, PhD
From the Gertrude H. Sergievsky Center (S.M.A., T.T.), Columbia University, New York, NY; Interdisciplinary Center for Palliative Medicine (M.W., G.D.B.), University of Munich, Munich, Germany; and Department of Neurology (V.E.D.), Tel-Aviv Sourasky Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
M. Wasner, MA
From the Gertrude H. Sergievsky Center (S.M.A., T.T.), Columbia University, New York, NY; Interdisciplinary Center for Palliative Medicine (M.W., G.D.B.), University of Munich, Munich, Germany; and Department of Neurology (V.E.D.), Tel-Aviv Sourasky Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
T. Tider, MSW
From the Gertrude H. Sergievsky Center (S.M.A., T.T.), Columbia University, New York, NY; Interdisciplinary Center for Palliative Medicine (M.W., G.D.B.), University of Munich, Munich, Germany; and Department of Neurology (V.E.D.), Tel-Aviv Sourasky Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
V. E. Drory, MD
From the Gertrude H. Sergievsky Center (S.M.A., T.T.), Columbia University, New York, NY; Interdisciplinary Center for Palliative Medicine (M.W., G.D.B.), University of Munich, Munich, Germany; and Department of Neurology (V.E.D.), Tel-Aviv Sourasky Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
G. D. Borasio, MD
From the Gertrude H. Sergievsky Center (S.M.A., T.T.), Columbia University, New York, NY; Interdisciplinary Center for Palliative Medicine (M.W., G.D.B.), University of Munich, Munich, Germany; and Department of Neurology (V.E.D.), Tel-Aviv Sourasky Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

Notes

Address correspondence and reprint requests to Dr. Steven M. Albert, Department of Behavioral and Community Health Sciences, Graduate School of Public Health, University of Pittsburgh, A211 Crabtree, 130 DeSoto Street, Pittsburgh, PA 15261; e-mail: [email protected]

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Cited By
  1. Assessing the Will to Live: A Scoping Review, Journal of Pain and Symptom Management, 61, 4, (845-857.e18), (2021).https://doi.org/10.1016/j.jpainsymman.2020.09.012
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  2. Epidemiology of Amyotrophic Lateral Sclerosis: A Population-Based Study in Israel, Neuroepidemiology, 47, 2, (76-81), (2016).https://doi.org/10.1159/000448921
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  3. Cultural Diversity, Families, and Research Subjects, The American Journal of Bioethics, 11, 5, (33-34), (2011).https://doi.org/10.1080/15265161.2011.560354
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  4. Psychiatric Nurses’ Expertise, Interest in End-of-Life Care, and Requests for Continuing Education on End of Life, American Journal of Hospice and Palliative Medicine®, 27, 1, (24-30), (2009).https://doi.org/10.1177/1049909109341873
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  5. Study Finds Cross-Cultural Variation in Mental Health at End of Life in Patients With Amyotrophic Lateral Sclerosis, Journal of Hospice & Palliative Nursing, 10, 2, (69), (2008).https://doi.org/10.1097/01.NJH.0000306727.93602.90
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  7. Assessing Quality of Life in ALS, Journal of Clinical Neuromuscular Disease, 9, 2, (318-325), (2007).https://doi.org/10.1097/CND.0b013e31815af9b7
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