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Clinical and Ethical Challenges
April 15, 2013

Management of unruptured intracranial aneurysms

Summary

Unruptured intracranial aneurysms (UIA) are a common finding, occurring in about 2% of the population, making them very likely to be seen by most practitioners, and present a challenge in the recommendations for optimal management and screening. The consequences of aneurysm rupture are dire, with high likelihood of significant morbidity and mortality. Most aneurysms do not rupture and patients harboring these lesions often remain asymptomatic. There are effective surgical and endovascular interventions to prevent rupture, but these procedures carry a risk of adverse complications. This article addresses the challenges of screening and management of UIAs.

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Information & Authors

Information

Published In

Neurology® Clinical Practice
Volume 3Number 2April 2013
Pages: 99-108

Publication History

Published in issue: April 2013
Published online: April 15, 2013

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Disclosures

The authors report no disclosures relevant to the manuscript. Go to Neurology.org/cp for full disclosures.

Study Funding

No targeted funding reported.

Authors

Affiliations & Disclosures

Lindsy N. Williams, MD
Department of Neurology, Mayo Clinic, Rochester, MN.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Robert D. Brown, Jr, MD, MPH
Department of Neurology, Mayo Clinic, Rochester, MN.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
LWW publisher, Handbook of Stroke, 2005 Mayo Clinic Press, Mayo Clinic Internal Medicine Board Review
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
Neilsen Foundation, Board of Directors, 2007-current Brain Aneurysm Foundation, Medical Advisory Board, 2009- current Joe Neikro Foundation for Aneurysm Research, Medical Advisory Board, 2011-
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
National Institutes of Health, NINDS -International Study of Unruptured Intracranial Aneurysms, ongoing, Principal Investigator -Familial Intracranial Aneurysm study, ongoing, Co-I -Siblings with Ischemic Stroke Study, ongoing, Co-I -Stroke Genetics Consortium, ongoing, Co-I Mayo Clinic-Czech Republic Research Collaboration -Stroke Project, Co-PI
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE

Notes

Correspondence to: [email protected]

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