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Contemporary Issues
April 6, 2020
Letter to the Editor

Preparing a neurology department for SARS-CoV-2 (COVID-19)
Early experiences at Columbia University Irving Medical Center and the New York Presbyterian Hospital in New York City

May 19, 2020 issue
94 (20) 886-891

Abstract

Beginning in December 2019, a novel coronavirus, SARS-CoV-2 (COVID-19), began spreading rapidly throughout China and now is a global pandemic, with cases reported in over 192 countries and territories worldwide. Clinically, COVID-19 ranges from a mild, self-limiting respiratory illness to severe progressive pneumonia and multiorgan failure. The first COVID-19 case was reported at the beginning of March in New York City (NYC), and now just 3 weeks later, NYC and its suburbs have over 5% of global cases. Worldwide, there is a rapid increase in the number of cases daily, including the number of patients requiring hospitalization and intensive care support.

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Letters to the Editor
17 April 2020
Reader response: Preparing a neurology department for SARS-CoV-2 (COVID-19): Early experiences at Columbia University Irving Medical Center and the New York Presbyterian Hospital in New York City
Larry B. Goldstein, Chair, Department of Neurology| University of Kentucky

Dr. Waldman and colleagues provide a helpful review of their department’s approach to addressing the impact of the COVID-19 pandemic on their programs and operations.1 Several of the themes they discuss are widely applicable with the understanding that each department also faces unique challenges in this setting.

Planning for a potential large surge of patients with COVID-19, the University of Kentucky Department of Neurology also needed to develop flexible staffing models to provide appropriate care for patients with neurologic disorders but also needed to simultaneously prepare for the need for neurology faculty, residents, and staff to be directly involved in COVID-19 related care. Adapting ambulatory TeleHealth technology to support resident continuity clinics and identifying strategies for addressing the needs of patients without broadband access were additional issues. We rapidly developed processes to support E-rounding on all our inpatient services to allow full participation in team rounding while minimizing the numbers of providers and staff in hallways and having direct patient contact. TeleHealth was also adapted to allow follow-up of research participants enrolled in therapeutic trials in their homes whenever feasible. All our educational programs were transitioned to interactive e-learning platforms.

As was stressed in the response at Columbia University, active faculty, trainee, and staff communication and engagement are critical. Since the start of the crisis, we have provided daily e-mail, neurology department specific summaries of plans, available resources, and initiatives, including offerings to support personal health and well-being. Continuing to share best practices will be critical as the academic neurology community faces this current challenge and its aftermath.

Disclosure

The author reports no relevant disclosures. Contact [email protected] for full disclosures.

Reference

  1. Waldman G, Mayeux R, Claassen J, et al. Preparing a neurology department for SARS-CoV-2 (COVID-19): Early experiences at Columbia University Irving Medical Center and the New York Presbyterian Hospital in New York City. Neurology 2020 Epub Apr 6.

Information & Authors

Information

Published In

Neurology®
Volume 94Number 20May 19, 2020
Pages: 886-891
PubMed: 32253352

Publication History

Received: March 27, 2020
Accepted: April 1, 2020
Published online: April 6, 2020
Published in print: May 19, 2020

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Disclosure

The authors report no relevant disclosures. Go to Neurology.org/N for full disclosures.

Study Funding

No targeted funding reported.

Authors

Affiliations & Disclosures

Genna Waldman, MD
From the Department of Neurology (G.W., R.M., J.C., S.A., J.W., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), Neurological Institute, Columbia University Irving Medical Center; and New York Presbyterian Hospital (G.W., R.M., J.C., S.A., J.W., E.A., P.P., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), New York, NY.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Richard Mayeux, MD, MS
From the Department of Neurology (G.W., R.M., J.C., S.A., J.W., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), Neurological Institute, Columbia University Irving Medical Center; and New York Presbyterian Hospital (G.W., R.M., J.C., S.A., J.W., E.A., P.P., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), New York, NY.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
Consultant to the Alzheimer's Disease Center at Rush University Medical School
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
RF1AG054023 Genetic Epidemiology of Cerebrovascular Factors in Alzheimer's Disease
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Jan Claassen, MD, PhD, FNCS
From the Department of Neurology (G.W., R.M., J.C., S.A., J.W., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), Neurological Institute, Columbia University Irving Medical Center; and New York Presbyterian Hospital (G.W., R.M., J.C., S.A., J.W., E.A., P.P., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), New York, NY.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
Editorial board of Neurocritical Care and Annals of Neurology
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
(1) NIH/NINDS, PI, R01 NS106014, Year 1 (2) NIH/NINDS, PI, R03 NS112760, Year 1 (3) NIH / NLM, Co-I and Site-PI, R01LM012734 (Albers) (4) NIH / NLM, Co-I and Site-PI, R01 LM011826 (Kleinberg) (5) NIH, Site-PI, U54NS100064 (Toga) (6) NIH, Site-PI, U01NS062835-06 (Johnston)
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
DANA foundation Stock/Stock Options, Medical Equipment & Materials: iCE Neurosystems, minority shareholder, 2018
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Sachin Agarwal, MD, MPH
From the Department of Neurology (G.W., R.M., J.C., S.A., J.W., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), Neurological Institute, Columbia University Irving Medical Center; and New York Presbyterian Hospital (G.W., R.M., J.C., S.A., J.W., E.A., P.P., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), New York, NY.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
From the Department of Neurology (G.W., R.M., J.C., S.A., J.W., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), Neurological Institute, Columbia University Irving Medical Center; and New York Presbyterian Hospital (G.W., R.M., J.C., S.A., J.W., E.A., P.P., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), New York, NY.
Disclosure
Scientific Advisory Boards:
1.
(1) Clinical endpoint committee, Reliant Heart, Commercial (2) Clinical endpoint committee, Cardiovascular Research Foundation, non--profit
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
Heartware incorporated (company bought by medtronic), Commercial entity
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
(1) Astra-Zeneca, local principal investigator, SOCRATES trial (ticagrelor versus aspirin for TIA/minor stroke) (2) Genentech, local principal investigator, PRISMS trial, TIMELESS trial (alteplase versus placebo for minor stroke)
Research Support, Government Entities:
1.
(1) NIH Funded by NINDS K 23 073 104, PI, July 2011 to June 2016. (2) NIH, local principal investigator, POINT trial (aspirin versus clopidogrel for minor stroke / TIA); SLEEPSMART (3) PCORI, local investigator, C3FIT trial
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Emily Anderson, MSN, RN, CNRN
From the Department of Neurology (G.W., R.M., J.C., S.A., J.W., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), Neurological Institute, Columbia University Irving Medical Center; and New York Presbyterian Hospital (G.W., R.M., J.C., S.A., J.W., E.A., P.P., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), New York, NY.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Patricia Punzalan, MA, RN, NE-BC
From the Department of Neurology (G.W., R.M., J.C., S.A., J.W., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), Neurological Institute, Columbia University Irving Medical Center; and New York Presbyterian Hospital (G.W., R.M., J.C., S.A., J.W., E.A., P.P., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), New York, NY.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Ryan Lichtcsien, MA
From the Department of Neurology (G.W., R.M., J.C., S.A., J.W., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), Neurological Institute, Columbia University Irving Medical Center; and New York Presbyterian Hospital (G.W., R.M., J.C., S.A., J.W., E.A., P.P., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), New York, NY.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Michelle Bell, MD
From the Department of Neurology (G.W., R.M., J.C., S.A., J.W., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), Neurological Institute, Columbia University Irving Medical Center; and New York Presbyterian Hospital (G.W., R.M., J.C., S.A., J.W., E.A., P.P., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), New York, NY.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
I am in contract with Demos Medical Publishing company for creation of a EEG tutorial atlas mobile app. The app has not been completed as yet and I have not received any royalties as yet. Also the details are being negotiated with Columbia University and all royalties might go to the University.
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Serge Przedborski, MD, PhD https://orcid.org/0000-0002-7283-3883
From the Department of Neurology (G.W., R.M., J.C., S.A., J.W., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), Neurological Institute, Columbia University Irving Medical Center; and New York Presbyterian Hospital (G.W., R.M., J.C., S.A., J.W., E.A., P.P., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), New York, NY.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
eLife, Reviewing editor, 3 yearsJournal of Neuroimmune Pharmacology, Editorial Board member, 10 yearsJournal of Parkinson?s disease, Editorial Board member, 4 yearsNeuroscience Next, Advisory Editorial Board member, 1 year
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
Trustee, Barnard College, Columbia University
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
1 R01 NS 107442 (Przedborski)09/01/2018 ? 06/30/20231.80 calendarNIH/NINDS$260,687Mechanisms of Axon Pathology in ALSThe major goal of this project is to determine the importance of protein prenylation in the motor axon growth and integrity and to identify the main targets of prenylation involved in this effect.R01 NS107442-02S1 (Przedborski)08/01/2019 ? 07/31/20201.20 calendarNIH/NINDS$242,207Protein prenylation inhibition for the treatment of tauopathiesEmerging evidence indicates that a protein modification process called protein prenylation plays an important role in the development of Alzheimer?s disease. This project is designed to unravel the contribution of protein prenylation to the progression of Alzheimer?s disease.1 R21 NS 111176 (Przedborski)04/01/2019 ? 03/31/2021 1.20 calendarNIH/NINDS$150,000Focused ultrasound and synucleinopathyWe propose to use a new noninvasive ultrasound technology to facilitate the entry of antibodies into the brain to block and clear abnormal alpha-synuclein. If successful, this strategy may have far-reaching implications for the treatment of Parkinson?s disease and related conditions.1 R21 AG 064596 (Przedborski) 08/01/2019 ? 06/30/2021 1.20 calendarNIH/NINDS $75,000A transcriptomic atlas of immune cells in a model of synucleinopathyTo establish an integrated approach to capture the immune cell signature associated with α-syn-related neurodegeneration at a single cell resolution and to use this knowledge for subsequent biomarker development and neuroprotective purposes in patients with synucleinopathies associated with dementia such as PDD and BLD.
Research Support, Foundations and Societies:
1.
Pre-Clinical Core Program (Przedborski)11/16/2018 ? 11/15/2021 0.60 calendar Project ALS $381,352In Vivo TestingThe pre-clinical core program is a multi-unit structure directed by selected experts to identify and test potential neuroprotective drugs that will be assessed first in cellular and vertebrate models of ALS.PF-RCE-1948 (Przedborski)07/01/2019 ? 06/30/2020 0.60 calendarParkinson?s Foundation$454,546Differential neuronal susceptibility as an avenue toward disease-modifying therapy for ParkinsonThe major goal is to establish an integrated approach that leverages this differential neuronal susceptibility to capture a multidimensional signature associated with PD neurodegeneration and to use this knowledge for subsequent development of biomarkers and neuroprotective strategies for PD and related conditions.
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Christina Ulane, MD, PhD
From the Department of Neurology (G.W., R.M., J.C., S.A., J.W., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), Neurological Institute, Columbia University Irving Medical Center; and New York Presbyterian Hospital (G.W., R.M., J.C., S.A., J.W., E.A., P.P., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), New York, NY.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
1. Iqvia and Takeda, 2) Travel compensation for Investigator Meeting for ADVANCE CIDP 1 NA Investigator meeting (trial for subcutaneous IG for the treatment of CIDP)
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
1) Lupin Family Foundation grant for studying epilepsy appointment clinic adherence 2) AAN Education Grant for studying patient centered communication
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Kirk Roberts, MD
From the Department of Neurology (G.W., R.M., J.C., S.A., J.W., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), Neurological Institute, Columbia University Irving Medical Center; and New York Presbyterian Hospital (G.W., R.M., J.C., S.A., J.W., E.A., P.P., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), New York, NY.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Olajide Williams, MD
From the Department of Neurology (G.W., R.M., J.C., S.A., J.W., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), Neurological Institute, Columbia University Irving Medical Center; and New York Presbyterian Hospital (G.W., R.M., J.C., S.A., J.W., E.A., P.P., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), New York, NY.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NIH/NINDS 2R01NS067443-06, Role PI, 03/01/16 – 03/31/21 NIH/NINR 1R01NR017571-01, Role PI, 09/24/18 - 06/30/23
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Andrew B. Lassman, MD
From the Department of Neurology (G.W., R.M., J.C., S.A., J.W., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), Neurological Institute, Columbia University Irving Medical Center; and New York Presbyterian Hospital (G.W., R.M., J.C., S.A., J.W., E.A., P.P., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), New York, NY.
Disclosure
Scientific Advisory Boards:
1.
Unrelated to the study (1) Karyopharm, (2) Sapience, (3) Abbott Molecular, (4) QED, (5) Bayer, (6) Orbus, (7) NW Bio, (8) AbbVie, (9) Agios, (10) Forma, (11) American Society of Clinical Oncology, (12) WebMD
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
(1) FDA, (2) National Brain Tumor Society, (3) Global Coalition for Adaptive Research, (4) Oncoceutics, (5) NRG Oncology Foundation, (6) Travel for activities in #1 above
Editorial Boards:
1.
(1) Neuro Oncology, Editorial Board, 2015-present (uncompensated), (2) Journal of Neurooncology, Editorial Board, 2009-present (uncompensated)
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
(1) Genentech/Roche, (2) Amgen, (3) Abbvie,(4) Millenium, (5) Celldex, (6) Novartis, (7) Pfizer, (8), Aeterna Zenaris, (9) Novartis, (10) QED, (11) Karyopharm, (12) Kadmon, (13) VBI Vaccines, (14) Beigene (15) Oncoceutics, (16), Bayer, (17) Agios, (18) Orbus
Research Support, Government Entities:
1.
(1) NCI/NIH P30 CA013696, role Associate Director, Herbert Irving Comprehensive Cancer Center and Medical Director, CPDM), (2) NIH/NCI UG1CA189960, role PI
Research Support, Academic Entities:
1.
(1) UCLA, (2) Northwestern
Research Support, Foundations and Societies:
1.
(1) Radiation Therapy Oncology Group Foundation, (2) Accelerate Brain Cancer Cure, (3) Voices Against Brain Cancer
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Laura Lennihan, MD
From the Department of Neurology (G.W., R.M., J.C., S.A., J.W., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), Neurological Institute, Columbia University Irving Medical Center; and New York Presbyterian Hospital (G.W., R.M., J.C., S.A., J.W., E.A., P.P., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), New York, NY.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Kiran T. Thakur, MD
From the Department of Neurology (G.W., R.M., J.C., S.A., J.W., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), Neurological Institute, Columbia University Irving Medical Center; and New York Presbyterian Hospital (G.W., R.M., J.C., S.A., J.W., E.A., P.P., R.L., M.B., S.P., C.U., K.R., O.W., A.B.L., L.L., K.T.T.), New York, NY.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
World Health Organization
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NICHD/NIH 1R01HD074944-01, NINDS K23 NS105935-01
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE

Notes

Correspondence Dr. Thakur [email protected]
Go to Neurology.org/N for full disclosures. Funding information and disclosures deemed relevant by the authors, if any, are provided at the end of the article.

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