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Abstract

Objective

Individualized patient selection for mechanical thrombectomy (MT) in patients with acute ischemic stroke (AIS) and large ischemic core (LIC) at baseline is an unmet need. We tested the hypothesis that assessing the functional relevance of both infarcted and hypoperfused brain tissue would improve the selection framework of patients with LIC for MT.

Methods

We performed a multicenter, retrospective study of adults with LIC (ischemic core volume >70 mL on MRI diffusion-weighted imaging) with MRI perfusion treated with MT or best medical management (BMM). Primary outcome was 3-month modified Rankin Scale (mRS), favorable if 0–3. Global and regional eloquence-based core perfusion mismatch ratios were derived. The predictive accuracy for clinical outcome of eloquent regions involvement was compared in multivariable and bootstrap random forest models.

Results

A total of 138 patients with baseline LIC were included (MT n = 96 or BMM n = 42; mean age ± SD, 72.4 ± 14.4 years; 34.1% female; mRS 0–3: 45.1%). Mean core and critically hypoperfused volume were 100.4 mL ± 36.3 mL and 157.6 ± 56.2 mL, respectively, and did not differ between groups. Models considering the functional relevance of the infarct location showed a better accuracy for the prediction of mRS 0–3 with a c statistic of 0.76 and 0.83 for logistic regression model and bootstrap random forest testing sets, respectively. In these models, the interaction between treatment effect of MT and the mismatch was significant (p = 0.04). In comparison, in the logistic regression model disregarding functional eloquence, the c statistic was 0.67 and the interaction between MT and the mismatch was insignificant.

Conclusions

Considering functional eloquence of hypoperfused tissue in patients with a large infarct core at baseline allows for a more precise estimation of treatment expected benefit.

Classification of Evidence

This study provides Class II evidence that, in patients with AIS and LIC, considering the functional eloquence of the infarct location improves prediction of disability status at 3 months.

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Information & Authors

Information

Published In

Neurology®
Volume 97Number 20November 16, 2021
Pages: e1975-e1985
PubMed: 34649871

Publication History

Received: January 28, 2021
Accepted: August 19, 2021
Published online: October 14, 2021
Published in print: November 16, 2021

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Disclosure

The authors report no disclosures. Go to Neurology.org/N for full disclosures.

Study Funding

The authors report no targeted funding.

Authors

Affiliations & Disclosures

Basile Kerleroux, MD*
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
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Kévin Janot, MD
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
None
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
None
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
None
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Dimitri Daly Eraya, MD
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
François Zhu, MD
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
None
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
None
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
None
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
None
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
None
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
None
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Charline Perot, MD
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Lili Detraz, MD
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Romain Bourcier, MD, PhD
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Rouchaud Aymeric, MD, PhD
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
None
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
None
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
None
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
Medtronic, paid lecture Microvention, paid lecture
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Florent Gariel, MD
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Pasquale Mordasini, MD
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Pierre Seners, MD, PhD
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
Guerbet France (speaker honoraria)
Editorial Boards:
1.
Associate editor for Frontiers in Neurology (stroke section, 2017-2021)
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Johannes Kaesmacher, MD
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
Frontiers in Neurology, Associate Editor (Research Topic: Tandem occlusion) BMC Neurology, Associate Editor
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
Swiss Stroke Society: Research Grant 2018 (
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
Non-profit entities : multicenter THRACE study (coordinator of the image reading comitee), ACTRIS multicenter study (image reading comitee), PROFILE- ARCADIA study (image reading comitee), SONOKID study
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
Canon, travel expenses (ECR congress)2019
Editorial Boards:
1.
Member of Editorial board of Diagnostic and interventional Imaging (2012-17)
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
Olivier Naggara, MD, PhD https://orcid.org/0000-0002-9544-379X
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.
Disclosure
Scientific Advisory Boards:
1.
NONE
Gifts:
1.
NONE
Funding for Travel or Speaker Honoraria:
1.
NONE
Editorial Boards:
1.
NONE
Patents:
1.
NONE
Publishing Royalties:
1.
NONE
Employment, Commercial Entity:
1.
NONE
Consultancies:
1.
NONE
Speakers' Bureaus:
1.
NONE
Other Activities:
1.
NONE
Clinical Procedures or Imaging Studies:
1.
NONE
Research Support, Commercial Entities:
1.
NONE
Research Support, Government Entities:
1.
NONE
Research Support, Academic Entities:
1.
NONE
Research Support, Foundations and Societies:
1.
NONE
Stock/stock Options/board of Directors Compensation:
1.
NONE
License Fee Payments, Technology or Inventions:
1.
NONE
Royalty Payments, Technology or Inventions:
1.
NONE
Stock/stock Options, Research Sponsor:
1.
NONE
Stock/stock Options, Medical Equipment & Materials:
1.
NONE
Legal Proceedings:
1.
NONE
on behalf of the JENI Research Collaborative
From INSERM U1266 (B.K., J.B., W.B.H., C.O., O.N.), Institut of Psychiatry and Neuroscience (IPNP), UMR_S1266, INSERM, Université de Paris, GHU Paris Psychiatrie et Neurosciences, Site Sainte-Anne; Diagnostic and Therapeutic Neuroradiology (K.J., G.B.), CHRU de Tours; Department of Interventional Neuroradiology (C.D., D.D.E.), University Hospital Center of Montpellier, Gui de Chauliac Hospital; Department of Diagnostic and Therapeutic Neuroradiology, CHRU-Nancy (F.Z., B.G.), IADI, INSERM U1254 (F.Z., B.G.), and ADI U1254 (F.Z., G.B.) Université de Lorraine, Nancy; Department of Diagnostic and Interventional Neuroradiology (J.-F.H.) and Neurology Department (C.P.), APHM, Cedex, Timone Hospital, Aix Marseille University; Department of Diagnostic and Interventional Neuroradiology (L.D., R.B.), Guillaume et René Laennec University Hospital, Nantes; Department of Interventional Neuroradiology (R.A., G.F.), Dupuytren University Hospital, Limoges; Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), Pellegrin Hospital–University Hospital of Bordeaux, France; Institute of Diagnostic, Interventional and Pediatric Radiology and Institute of Diagnostic and Interventional Neuroradiology (P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Switzerland; Neurology Department (P.S.), Fondation Rothschild Hospital, Paris; Neurology Department (G.T.), GHU Paris Psychiatrie et Neurosciences, Université de Paris, INSERM U1266, FHU NeuroVasc; and Neuroradiology Department (G.B.), Université de Paris, des Neurosciences Psychiatrie de Paris, France.

Notes

Correspondence Dr. Kerleroux [email protected]
Go to Neurology.org/N for full disclosures. Funding information and disclosures deemed relevant by the authors, if any, are provided at the end of the article.
*
B. Kerleroux and J. Benzakoun contributed equally to this work as co–first authors.
JENI Research Collaborative coinvestigators are listed at links.lww.com/WNL/B588

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