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Abstract

Objectives

To estimate the number of cases and deaths related to hemorrhagic stroke (HS) attributable to a chronic alcohol consumption and to heavy episodic drinking (HED) in France.

Methods

A population-attributable fraction (PAF) estimation approach was used. Relative risks for HS with alcohol consumption were extracted from the INTERSTROKE study. Levels of alcohol consumption in the French population were collected from the 2017 Health Barometer. Data on HS morbidity and mortality were extracted from the French National Health Data System (SNDS).

Results

We estimated that 7.2% (n = 2,100) and 6.6% (n = 1,900) of cases with HS were attributable to chronic alcohol consumption and HED, respectively. PAFs were higher in men than in women with 11.5% vs 2.6% for a chronic consumption and 10.7% vs 2.1% for HED, respectively. We estimated that 7.0% of HS deaths (n = 1,100) were attributable to chronic alcohol consumption and 5.1% attributable to HED (n = 800). Finally, 16.3% of patients with HS (n = 4,700) and 14.1% of HS deaths (n = 2,300) were attributable to overall chronic alcohol consumption or to monthly HED.

Discussion

These results remind the importance of alcohol consumption in the occurrence of HS and the importance of implementing primary and secondary prevention measures, particularly among young people, where HED is most common.

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Supplementary Material

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References

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Information & Authors

Information

Published In

Neurology®
Volume 102Number 8April 23, 2024
PubMed: 38527250

Publication History

Received: November 13, 2023
Accepted: December 20, 2023
Published online: March 25, 2024
Published in issue: April 23, 2024

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Disclosure

The authors report no relevant disclosures. Go to Neurology.org/N for full disclosures.

Study Funding

The authors report no targeted funding.

Authors

Affiliations & Disclosures

From the French Public Health Agency (L.D., C.G., C.B., P.J., R.A., G.Q., V.N.-T., V.O., A.G.), Saint-Maurice; and Univ. Bordeaux (P.J.), ISPED, INSERM, Bordeaux Population Health Research Center, UMR 1219, Bordeaux, France.
Disclosure
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NONE
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NONE
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NONE
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NONE
From the French Public Health Agency (L.D., C.G., C.B., P.J., R.A., G.Q., V.N.-T., V.O., A.G.), Saint-Maurice; and Univ. Bordeaux (P.J.), ISPED, INSERM, Bordeaux Population Health Research Center, UMR 1219, Bordeaux, France.
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Christophe Bonaldi, PhD
From the French Public Health Agency (L.D., C.G., C.B., P.J., R.A., G.Q., V.N.-T., V.O., A.G.), Saint-Maurice; and Univ. Bordeaux (P.J.), ISPED, INSERM, Bordeaux Population Health Research Center, UMR 1219, Bordeaux, France.
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NONE
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NONE
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Pierre Joly, PhD
From the French Public Health Agency (L.D., C.G., C.B., P.J., R.A., G.Q., V.N.-T., V.O., A.G.), Saint-Maurice; and Univ. Bordeaux (P.J.), ISPED, INSERM, Bordeaux Population Health Research Center, UMR 1219, Bordeaux, France.
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NONE
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Raphaël Andler, MS
From the French Public Health Agency (L.D., C.G., C.B., P.J., R.A., G.Q., V.N.-T., V.O., A.G.), Saint-Maurice; and Univ. Bordeaux (P.J.), ISPED, INSERM, Bordeaux Population Health Research Center, UMR 1219, Bordeaux, France.
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Governmental - Santé publique France: I currently work as research manager for Santé publique France in the field of addictions
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Guillemette Quatremere, MS
From the French Public Health Agency (L.D., C.G., C.B., P.J., R.A., G.Q., V.N.-T., V.O., A.G.), Saint-Maurice; and Univ. Bordeaux (P.J.), ISPED, INSERM, Bordeaux Population Health Research Center, UMR 1219, Bordeaux, France.
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Viêt Nguyen-Thanh, MS
From the French Public Health Agency (L.D., C.G., C.B., P.J., R.A., G.Q., V.N.-T., V.O., A.G.), Saint-Maurice; and Univ. Bordeaux (P.J.), ISPED, INSERM, Bordeaux Population Health Research Center, UMR 1219, Bordeaux, France.
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Valérie Olié, PhD
From the French Public Health Agency (L.D., C.G., C.B., P.J., R.A., G.Q., V.N.-T., V.O., A.G.), Saint-Maurice; and Univ. Bordeaux (P.J.), ISPED, INSERM, Bordeaux Population Health Research Center, UMR 1219, Bordeaux, France.
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NONE
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NONE
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From the French Public Health Agency (L.D., C.G., C.B., P.J., R.A., G.Q., V.N.-T., V.O., A.G.), Saint-Maurice; and Univ. Bordeaux (P.J.), ISPED, INSERM, Bordeaux Population Health Research Center, UMR 1219, Bordeaux, France.
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Notes

Correspondence Dr. Gabet [email protected]
Go to Neurology.org/N for full disclosures. Funding information and disclosures deemed relevant by the authors, if any, are provided at the end of the article.
Submitted and externally peer reviewed. The handling editor was Editor-in-Chief José Merino, MD, MPhil, FAAN.

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