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Abstract

Article abstract—We administered the Mini-Mental State Exam (MMSE) to 194 healthy men and women, ages 40 to 89 years. Total score was significantly associated with age (p < 0.0001), but not vocabulary, education, Beck's Depression Inventory Score, or sex. The lowest quartile cutoff scores for the MMSE by decade were 40s −29; 50s −28; 60s −28; 70s −28; and 80s −26. When screening for progressive decline in cognitive performance, the use of age-specific norms may provide greater sensitivity than the present recommended cutoff score of less than 24.

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Published In

Neurology®
Volume 38Number 10October 1988
Pages: 1565
PubMed: 3419600

Publication History

Published online: October 1, 1988
Published in print: October 1988

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Margit L. Bleecker, MD, PhD
Department of Neurology (Drs. Bleecker, Bolla-Wilson, and Kawas), Francis Scott Key Medical Center, Johns Hopkins University School of Medicine; and the Department of Environmental Health Sciences (Drs. Bleecker and Agnew), Division of Occupational Medicine, Johns Hopkins University, School of Hygiene and Public Health, Baltimore, MD.
Karen Bolla-Wilson, PhD
Department of Neurology (Drs. Bleecker, Bolla-Wilson, and Kawas), Francis Scott Key Medical Center, Johns Hopkins University School of Medicine; and the Department of Environmental Health Sciences (Drs. Bleecker and Agnew), Division of Occupational Medicine, Johns Hopkins University, School of Hygiene and Public Health, Baltimore, MD.
Claudia Kawas, MD
Department of Neurology (Drs. Bleecker, Bolla-Wilson, and Kawas), Francis Scott Key Medical Center, Johns Hopkins University School of Medicine; and the Department of Environmental Health Sciences (Drs. Bleecker and Agnew), Division of Occupational Medicine, Johns Hopkins University, School of Hygiene and Public Health, Baltimore, MD.
Jacqueline Agnew, PhD
Department of Neurology (Drs. Bleecker, Bolla-Wilson, and Kawas), Francis Scott Key Medical Center, Johns Hopkins University School of Medicine; and the Department of Environmental Health Sciences (Drs. Bleecker and Agnew), Division of Occupational Medicine, Johns Hopkins University, School of Hygiene and Public Health, Baltimore, MD.

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