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Brief Communications
November 27, 2001

Sustained excitability elevations induced by transcranial DC motor cortex stimulation in humans

November 27, 2001 issue
57 (10) 1899-1901


The authors show that in the human transcranial direct current stimulation is able to induce sustained cortical excitability elevations. As revealed by transcranial magnetic stimulation, motor cortical excitability increased approximately 150% above baseline for up to 90 minutes after the end of stimulation. The feasibility of inducing long-lasting excitability modulations in a noninvasive, painless, and reversible way makes this technique a potentially valuable tool in neuroplasticity modulation.

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Information & Authors


Published In

Volume 57Number 10November 27, 2001
Pages: 1899-1901
PubMed: 11723286

Publication History

Received: April 16, 2001
Accepted: July 14, 2001
Published online: November 27, 2001
Published in print: November 27, 2001


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Affiliations & Disclosures

Michael A. Nitsche, MD
From the Department of Clinical Neurophysiology, University of Goettingen, Germany.
Walter Paulus, MD
From the Department of Clinical Neurophysiology, University of Goettingen, Germany.


Address correspondence and reprint requests to Dr. W. Paulus, Department of Clinical Neurophysiology, University of Goettingen, Robert Koch Str. 40, 37075 Goettingen, Germany; e-mail: [email protected]

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