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Abstract

The authors evaluated the long-term clinical outcome of neurosarcoidosis and determined predictive factors of disease course. Twenty-seven patients with neurosarcoidosis were followed for at least 5 years from the onset of neurologic symptoms. Patients with CNS involvement during the course of the disease had a higher Modified Oxford Handicap Scale score than those with peripheral nervous system involvement (p < 0.02). CNS involvement may be a predictive factor for a less favorable disease course. Early and intensive treatment should be considered in such cases.

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Published In

Neurology®
Volume 57Number 5September 11, 2001
Pages: 927-929
PubMed: 11552036

Publication History

Received: January 4, 2001
Accepted: April 24, 2001
Published online: September 11, 2001
Published in print: September 11, 2001

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Authors

Affiliations & Disclosures

D. Ferriby, MD
From the Departments of Neurology (Drs. Ferriby, de Seze, Stojkovic, Destée, and Vermersch), Internal Medicine (Drs. Hachulla and Hatron), and Pneumology (Dr. Wallaert), CHRU de Lille, France.
J. de Seze, MD
From the Departments of Neurology (Drs. Ferriby, de Seze, Stojkovic, Destée, and Vermersch), Internal Medicine (Drs. Hachulla and Hatron), and Pneumology (Dr. Wallaert), CHRU de Lille, France.
T. Stojkovic, MD
From the Departments of Neurology (Drs. Ferriby, de Seze, Stojkovic, Destée, and Vermersch), Internal Medicine (Drs. Hachulla and Hatron), and Pneumology (Dr. Wallaert), CHRU de Lille, France.
E. Hachulla, MD
From the Departments of Neurology (Drs. Ferriby, de Seze, Stojkovic, Destée, and Vermersch), Internal Medicine (Drs. Hachulla and Hatron), and Pneumology (Dr. Wallaert), CHRU de Lille, France.
B. Wallaert, MD
From the Departments of Neurology (Drs. Ferriby, de Seze, Stojkovic, Destée, and Vermersch), Internal Medicine (Drs. Hachulla and Hatron), and Pneumology (Dr. Wallaert), CHRU de Lille, France.
A. Destée, MD
From the Departments of Neurology (Drs. Ferriby, de Seze, Stojkovic, Destée, and Vermersch), Internal Medicine (Drs. Hachulla and Hatron), and Pneumology (Dr. Wallaert), CHRU de Lille, France.
P. Y. Hatron, MD
From the Departments of Neurology (Drs. Ferriby, de Seze, Stojkovic, Destée, and Vermersch), Internal Medicine (Drs. Hachulla and Hatron), and Pneumology (Dr. Wallaert), CHRU de Lille, France.
P. Vermersch, MD
From the Departments of Neurology (Drs. Ferriby, de Seze, Stojkovic, Destée, and Vermersch), Internal Medicine (Drs. Hachulla and Hatron), and Pneumology (Dr. Wallaert), CHRU de Lille, France.

Notes

Address correspondence and reprint requests to Dr. D. Ferriby, Clinique Neurologique, Service de Neurologie D, Hôpital Roger Salengro, CHRU Lille, 59037 Lille Cedex; e-mail: [email protected]

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  8. Distinguishing CNS neurosarcoidosis from multiple sclerosis and an approach to “overlap” cases, Journal of Neuroimmunology, 369, (577904), (2022).https://doi.org/10.1016/j.jneuroim.2022.577904
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  10. Neurosarcoidosis: Phenotypes, Approach to Diagnosis and Treatment, Current Rheumatology Reports, 24, 12, (371-382), (2022).https://doi.org/10.1007/s11926-022-01089-z
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