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Brief Communications
February 12, 2002

False lateralization of language cortex on functional MRI after a cluster of focal seizures

February 12, 2002 issue
58 (3) 490-492


fMRI can define language cortex but its limitations are not yet fully understood. This article describes a child in whom fMRI falsely lateralized language cortex when performed after a cluster of left temporal lobe seizures. Multiple language tasks revealed no activation over the left temporal lobe despite a normal neurologic exam at the time of the study. A second fMRI performed 2 weeks later activated sites predominantly over the left, which were confirmed by extra-operative functional language mapping. fMRI may be unhelpful after frequent seizures.

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Information & Authors


Published In

Volume 58Number 3February 12, 2002
Pages: 490-492
PubMed: 11839861

Publication History

Received: June 7, 2001
Accepted: October 22, 2001
Published online: February 12, 2002
Published in print: February 12, 2002


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Affiliations & Disclosures

Prasanna Jayakar, MD PhD
From the Department of Neurology (Dr. Jayakar) and Radiology (Drs. Bernal, Medina, and Altman), Miami Children’s Hospital, Miami, FL.
Byron Bernal, MD
From the Department of Neurology (Dr. Jayakar) and Radiology (Drs. Bernal, Medina, and Altman), Miami Children’s Hospital, Miami, FL.
L. Santiago Medina, MD MPH
From the Department of Neurology (Dr. Jayakar) and Radiology (Drs. Bernal, Medina, and Altman), Miami Children’s Hospital, Miami, FL.
Nolan Altman, MD
From the Department of Neurology (Dr. Jayakar) and Radiology (Drs. Bernal, Medina, and Altman), Miami Children’s Hospital, Miami, FL.


Address correspondence and reprint requests to Dr. Prasanna Jayakar, Neuroscience Center, Miami Children’s Hospital, 3100 SW 62nd Avenue, Miami, FL 33155; e-mail: [email protected]

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