Neuropathologic evaluation of 40 confirmed cases of Legionella pneumonia
Abstract
Autopsy examination of the brain was performed in 40 cases of Legionella pneumonia. Thirty-nine of 40 patients had underlying chronic or acute medical problems. Sixteen patients (40%) had neurologic signs or symptoms that were not explained by preexisting disease. CSF was normal in six of seven patients examined; CSF protein content was 66 mg/100 ml in one patient. Neuropathologic examination in all 40 patients demonstrated no lesions attributable to disseminated Legionella pneumophila. Mechanisms other than direct cerebral invasion by the causative organism must be sought to explain the neurologic manifestations of Legionella pneumonia.
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© 1983 by the American Academy of Neurology.
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Published online: October 1, 1983
Published in print: October 1983
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- Legionnaires Disease With Focal Neurologic Deficits and a Reversible Lesion in the Splenium of the Corpus Callosum, Infectious Diseases in Clinical Practice, 25, 1, (13-18), (2017).https://doi.org/10.1097/IPC.0000000000000441
- Nervous System Abnormalities and Legionnaire’s Disease, Infectious Disease Clinics of North America, 31, 1, (55-68), (2017).https://doi.org/10.1016/j.idc.2016.10.005
- Two Cases of Legionella pneumophila Pneumonia with Prolonged Neurologic Symptoms and Brain Hypoperfusion on Single-Photon Emission Computed Tomography , Case Reports in Infectious Diseases, 2016, (1-4), (2016).https://doi.org/10.1155/2016/5264681
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- Forensic Aspects of Adult and General Neuropathology, Forensic Neuropathology, Third Edition, (89-262), (2014).https://doi.org/10.1201/b16882-4
- Bacterial infections, Greenfield's Neuropathology Eighth Edition. 2 Volume Set and DVD, (1391-1445), (2013).https://doi.org/10.1201/b13319-19
- Legionella micdadei Brain Abscess, Journal of Clinical Microbiology, 51, 2, (701-704), (2013).https://doi.org/10.1128/JCM.02160-12
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