The effects of pregnancy in multiple sclerosis
A retrospective study
Abstract
We reviewed the medical records of 178 women with multiple sclerosis to evaluate the number of completed pregnancies, current disability status, and relationship of pregnancy to onset of MS symptoms. We found no differences in the long-term disability of women with no pregnancies, one pregnancy, or two or more pregnancies. Women who had initial symptom onset in pregnancy experienced less subsequent disability than women whose symptoms began before or after pregnancy. Therefore, pregnancy per se or number of pregnancies has no effect on subsequent disability.
Get full access to this article
View all available purchase options and get full access to this article.
Information & Authors
Information
Published In
Copyright
© 1986 by the American Academy of Neurology.
Publication History
Published online: August 1, 1986
Published in print: August 1986
Authors
Metrics & Citations
Metrics
Citations
Download Citations
If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Select your manager software from the list below and click Download.
Cited By
- Parity is associated with long-term differences in DNA methylation at genes related to neural plasticity in multiple sclerosis, Clinical Epigenetics, 15, 1, (2023).https://doi.org/10.1186/s13148-023-01438-4
- Conceiving complexity: Biological mechanisms underpinning the lasting effect of pregnancy on multiple sclerosis outcomes, Autoimmunity Reviews, 22, 9, (103388), (2023).https://doi.org/10.1016/j.autrev.2023.103388
- A Pilot Study of the Effect upon Multiple Sclerosis of the Menopause, Hormone Replacement Therapy and the Menstrual Cycle, Journal of the Royal Society of Medicine, 85, 10, (612-613), (2022).https://doi.org/10.1177/014107689208501008
- Is pregnancy in MS patients safe and what is its impact on MS course? Real World evidence of 1533 pregnancies in Czech Republic, Multiple Sclerosis and Related Disorders, 59, (103391), (2022).https://doi.org/10.1016/j.msard.2021.103391
- Influence of Pregnancy in Multiple Sclerosis and Impact of Disease-Modifying Therapies, Frontiers in Neurology, 12, (2021).https://doi.org/10.3389/fneur.2021.697974
- The effects of pregnancy on relapse rates, disability and peripartum outcomes in women with multiple sclerosis: a systematic review and meta-analysis, Journal of Comparative Effectiveness Research, 10, 3, (175-186), (2021).https://doi.org/10.2217/cer-2020-0211
- Sex effects across the lifespan in women with multiple sclerosis, Therapeutic Advances in Neurological Disorders, 13, (2020).https://doi.org/10.1177/1756286420936166
- Pregnancy-related issues in women with multiple sclerosis: an evidence-based review with practical recommendations, Journal of Drug Assessment, 9, 1, (20-36), (2020).https://doi.org/10.1080/21556660.2020.1721507
- Pregnancy outcomes in Portuguese women with multiple sclerosis: The PREGNIMS study, Multiple Sclerosis and Related Disorders, 28, (172-176), (2019).https://doi.org/10.1016/j.msard.2018.12.033
- Pregnancy and multiple sclerosis: Clinical effects across the lifespan, Autoimmunity Reviews, 18, 10, (102360), (2019).https://doi.org/10.1016/j.autrev.2019.102360
- See more
Loading...
View Options
Login options
Check if you have access through your login credentials or your institution to get full access on this article.
Personal login Institutional LoginPurchase Options
The neurology.org payment platform is currently offline. Our technical team is working as quickly as possible to restore service.
If you need immediate support or to place an order, please call or email customer service:
- 1-800-638-3030 for U.S. customers - 8:30 - 7 pm ET (M-F)
- 1-301-223-2300 for customers outside the U.S. - 8:30 - 7 pm ET (M-F)
- [email protected]
We appreciate your patience during this time and apologize for any inconvenience.