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January 1, 1993

Antineuronal (anti‐Ri) antibodies in a patient with steroid‐responsive opsoclonus‐myoclonus

January 1993 issue
43 (1_part_1) 207

Abstract

A 45-year-old woman developed opsoclonus, myoclonus, and severe truncal and gait ataxia. Serum and CSF contained IgG antibodies that appear to be identical to “anti-Ri” antibodies associated with paraneoplastic opsoclonus and ataxia. The patient had a fluctuating course with exacerbations that responded well to corticosteroids and later to cyclophosphamide. Her anti-Ri antibody titer has declined significantly but still remains high. After more than 3 years of follow-up, no neoplasm has been detected.

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Information

Published In

Neurology®
Volume 43Number 1_part_1January 1993
Pages: 207
PubMed: 8423887

Publication History

Published online: January 1, 1993
Published in print: January 1993

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Authors

Affiliations & Disclosures

Edward J. Dropcho, MD
Departments of Neurology (Dr. Dropcho), and Ophthalmology (Dr. Kline), University of Alabama at Birmingham, and Birmingham Veterans Affairs Medical Center, and Brookwood Medical Center (Dr. Riser), Birmingham, AL.
Lanning B. Kline, MD
Departments of Neurology (Dr. Dropcho), and Ophthalmology (Dr. Kline), University of Alabama at Birmingham, and Birmingham Veterans Affairs Medical Center, and Brookwood Medical Center (Dr. Riser), Birmingham, AL.
John Riser, MD
Departments of Neurology (Dr. Dropcho), and Ophthalmology (Dr. Kline), University of Alabama at Birmingham, and Birmingham Veterans Affairs Medical Center, and Brookwood Medical Center (Dr. Riser), Birmingham, AL.

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Cited By
  1. Paraneoplastic Cerebellar Degeneration Associated with Breast Cancer: A Case Report and a Narrative Review, Brain Sciences, 14, 2, (176), (2024).https://doi.org/10.3390/brainsci14020176
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  2. Opsoclonus–myoclonus syndrome caused by organophosphate poisoning, Practical Neurology, 23, 3, (243-245), (2023).https://doi.org/10.1136/pn-2022-003612
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  3. Diagnosis and treatment of paraneoplastic neurological disorders, Neurological Complications of Systemic Cancer and Antineoplastic Therapy, (223-240), (2022).https://doi.org/10.1016/B978-0-12-821976-8.00029-3
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  4. Paraneoplastic neurological syndromes: clinical presentations and management, Therapeutic Advances in Neurological Disorders, 14, (2021).https://doi.org/10.1177/1756286420985323
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  5. Sleep Disturbances Associated with Neurological Autoimmunity, Neurotherapeutics, 18, 1, (181-201), (2021).https://doi.org/10.1007/s13311-021-01020-x
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  6. Clinical spectrum and diagnostic pitfalls of neurologic syndromes with Ri antibodies, Neurology Neuroimmunology & Neuroinflammation, 7, 3, (2020)./doi/10.1212/NXI.0000000000000699
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  7. Paraneoplastic opsoclonus-myoclonus syndrome in a patient with oesophageal adenocarcinoma, Neurología (English Edition), 35, 9, (677-678), (2020).https://doi.org/10.1016/j.nrleng.2019.09.005
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  8. Síndrome opsoclono-mioclono paraneoplásico en paciente con adenocarcinoma de esófago, Neurología, 35, 9, (677-678), (2020).https://doi.org/10.1016/j.nrl.2019.09.008
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  9. Paraneoplastic Neurologic Syndromes, Abeloff's Clinical Oncology, (676-687.e5), (2020).https://doi.org/10.1016/B978-0-323-47674-4.00044-X
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  10. Paraneoplastic Neurologic Disease, Neurorheumatology, (141-157), (2019).https://doi.org/10.1007/978-3-030-16928-2_15
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