Skip to main content
AAN.com
Brief Communications
September 26, 2000

Cognitive performance in surgically menopausal women on estrogen

September 26, 2000 issue
55 (6) 872-874

Abstract

Article abstract Estrogen replacement therapy (ERT) may help maintain normal cognitive function. Nondemented surgically menopausal women on ERT (n = 10) enrolled in a longitudinal aging study performed better than age- and education-matched control subjects (n = 25) on selected tests of verbal memory and constructional ability. These results suggest that ERT initiated soon after surgical menopause can have long-term neuroprotective effects in cognitively intact women.

Get full access to this article

View all available purchase options and get full access to this article.

References

1.
Yaffe K, Sawaya G, Lieberburg I, Grady D. Estrogen therapy in postmenopausal women: effects on cognitive function and dementia. JAMA . 1998; 279: 688–695.
2.
Sherwin BB. Estrogen effects on cognition in menopausal women. Neurology . 1997; 48 (suppl): S21–S26.
3.
Jacobs DM, Tang MX, Stern Y, et al. Cognitive function in nondemented older women who took estrogen after menopause. Neurology . 1998; 50: 368–373.
4.
Verghese J, Crystal HA, Dickson DW, Lipton RB. Validity of clinical criteria for the diagnosis of dementia with Lewy bodies. Neurology . 1999; 53: 1974–1982.
5.
Masur DM, Sliwinski M, Lipton RB, Blau AD, Crystal HA. Neuropsychological prediction of dementia and the absence of dementia in healthy elderly persons. Neurology . 1994; 44: 1427–1432.
6.
American Psychiatric Association. DSM-IV: diagnostic and statistical manual of mental disorders. 4th ed. Washington, DC: American Psychiatric Association, 1994.
7.
Buschke H. Cued recall in amnesia. J Clin Neuropsychol . 1984; 6; 433–440.
8.
Grober E, Sliwinski M. Development and validation of a model for estimating premorbid verbal intelligence in the elderly. J Clin Exp Neuropsychol . 1991; 13: 933–949.
9.
Phillips S, Sherwin BB. Effects of estrogen on memory function in surgically menopausal women. Psychoneuroendocrinology . 1992; 17: 485–495.
10.
Mulnard A, Cotman CW, Kawas C, et al. Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease. JAMA . 2000; 283: 1007–1015.

Information & Authors

Information

Published In

Neurology®
Volume 55Number 6September 26, 2000
Pages: 872-874
PubMed: 10994013

Publication History

Received: March 8, 2000
Accepted: May 25, 2000
Published online: September 26, 2000
Published in print: September 26, 2000

Permissions

Request permissions for this article.

Authors

Affiliations & Disclosures

J. Verghese, MD
From the Einstein Aging Study (Drs. Verghese, Kuslansky, Sliwinski, Crystal, Buschke, Lipton, and M. Katz), the Departments of Neurology (Drs. Verghese, Kuslansky, Sliwinski, Crystal, Buschke, Lipton, and M. Katz), and Epidemiology and Social Medicine (Dr. Lipton), Albert Einstein College of Medicine, Bronx, NY; and Innovative Medical Research (Dr. Lipton), Stamford, CT.
G. Kuslansky, PhD
From the Einstein Aging Study (Drs. Verghese, Kuslansky, Sliwinski, Crystal, Buschke, Lipton, and M. Katz), the Departments of Neurology (Drs. Verghese, Kuslansky, Sliwinski, Crystal, Buschke, Lipton, and M. Katz), and Epidemiology and Social Medicine (Dr. Lipton), Albert Einstein College of Medicine, Bronx, NY; and Innovative Medical Research (Dr. Lipton), Stamford, CT.
M.J. Katz, MPH
From the Einstein Aging Study (Drs. Verghese, Kuslansky, Sliwinski, Crystal, Buschke, Lipton, and M. Katz), the Departments of Neurology (Drs. Verghese, Kuslansky, Sliwinski, Crystal, Buschke, Lipton, and M. Katz), and Epidemiology and Social Medicine (Dr. Lipton), Albert Einstein College of Medicine, Bronx, NY; and Innovative Medical Research (Dr. Lipton), Stamford, CT.
M. Sliwinski, PhD
From the Einstein Aging Study (Drs. Verghese, Kuslansky, Sliwinski, Crystal, Buschke, Lipton, and M. Katz), the Departments of Neurology (Drs. Verghese, Kuslansky, Sliwinski, Crystal, Buschke, Lipton, and M. Katz), and Epidemiology and Social Medicine (Dr. Lipton), Albert Einstein College of Medicine, Bronx, NY; and Innovative Medical Research (Dr. Lipton), Stamford, CT.
H.A. Crystal, MD
From the Einstein Aging Study (Drs. Verghese, Kuslansky, Sliwinski, Crystal, Buschke, Lipton, and M. Katz), the Departments of Neurology (Drs. Verghese, Kuslansky, Sliwinski, Crystal, Buschke, Lipton, and M. Katz), and Epidemiology and Social Medicine (Dr. Lipton), Albert Einstein College of Medicine, Bronx, NY; and Innovative Medical Research (Dr. Lipton), Stamford, CT.
H. Buschke, MD
From the Einstein Aging Study (Drs. Verghese, Kuslansky, Sliwinski, Crystal, Buschke, Lipton, and M. Katz), the Departments of Neurology (Drs. Verghese, Kuslansky, Sliwinski, Crystal, Buschke, Lipton, and M. Katz), and Epidemiology and Social Medicine (Dr. Lipton), Albert Einstein College of Medicine, Bronx, NY; and Innovative Medical Research (Dr. Lipton), Stamford, CT.
R.B. Lipton, MD
From the Einstein Aging Study (Drs. Verghese, Kuslansky, Sliwinski, Crystal, Buschke, Lipton, and M. Katz), the Departments of Neurology (Drs. Verghese, Kuslansky, Sliwinski, Crystal, Buschke, Lipton, and M. Katz), and Epidemiology and Social Medicine (Dr. Lipton), Albert Einstein College of Medicine, Bronx, NY; and Innovative Medical Research (Dr. Lipton), Stamford, CT.

Notes

Address correspondence and reprint requests to Dr. Joe Verghese, Department of Neurology/Einstein Aging Study, Albert Einstein College of Medicine, 1165 Morris Park Avenue, Bronx, NY 10461; e-mail: [email protected]

Metrics & Citations

Metrics

Citation information is sourced from Crossref Cited-by service.

Citations

Download Citations

If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Select your manager software from the list below and click Download.

Cited By
  1. Physical activity and verbal memory performance: Mediating effects of resting-state brain activity, , (2024).https://doi.org/10.1016/bs.pbr.2024.01.006
    Crossref
  2. Antipsychotic-induced prolactin elevation in premenopausal women with schizophrenia: associations with estrogen, disease severity and cognition, Archives of Women's Mental Health, 27, 6, (931-941), (2024).https://doi.org/10.1007/s00737-024-01491-9
    Crossref
  3. Endogenous and Exogenous Estrogen Exposures: How Women’s Reproductive Health Can Drive Brain Aging and Inform Alzheimer’s Prevention, Frontiers in Aging Neuroscience, 14, (2022).https://doi.org/10.3389/fnagi.2022.831807
    Crossref
  4. Hormone therapy in the postmenopausal years: considering benefits and risks in clinical practice, Human Reproduction Update, 27, 6, (1115-1150), (2021).https://doi.org/10.1093/humupd/dmab026
    Crossref
  5. The Role of Estrogen Receptors and Their Signaling across Psychiatric Disorders, International Journal of Molecular Sciences, 22, 1, (373), (2020).https://doi.org/10.3390/ijms22010373
    Crossref
  6. Sex effects across the lifespan in women with multiple sclerosis, Therapeutic Advances in Neurological Disorders, 13, (2020).https://doi.org/10.1177/1756286420936166
    Crossref
  7. Xiao‐Yao‐San Formula Improves Cognitive Ability by Protecting the Hippocampal Neurons in Ovariectomized Rats, Evidence-Based Complementary and Alternative Medicine, 2020, 1, (2020).https://doi.org/10.1155/2020/4156145
    Crossref
  8. Neuropsychological Functioning of Endocrinology Disorders: Gonadotropic Hormones and Corticosteroids, Handbook of Medical Neuropsychology, (581-597), (2019).https://doi.org/10.1007/978-3-030-14895-9_26
    Crossref
  9. Cognitive Changes with Reproductive Aging, Perimenopause, and Menopause, Obstetrics and Gynecology Clinics of North America, 45, 4, (751-763), (2018).https://doi.org/10.1016/j.ogc.2018.07.011
    Crossref
  10. Effects of Age and Gender on Recall and Recognition Discriminability, Archives of Clinical Neuropsychology, 32, 8, (972-979), (2017).https://doi.org/10.1093/arclin/acx024
    Crossref
  11. See more
Loading...

View Options

Login options

Check if you have access through your login credentials or your institution to get full access on this article.

Personal login Institutional Login
Purchase Options

The neurology.org payment platform is currently offline. Our technical team is working as quickly as possible to restore service.

If you need immediate support or to place an order, please call or email customer service:

  • 1-800-638-3030 for U.S. customers - 8:30 - 7 pm ET (M-F)
  • 1-301-223-2300 for customers outside the U.S. - 8:30 - 7 pm ET (M-F)
  • [email protected]

We appreciate your patience during this time and apologize for any inconvenience.

View options

PDF and All Supplements

Download PDF and Supplementary Material

Full Text

View Full Text

Full Text HTML

View Full Text HTML

Figures

Tables

Media

Share

Share

Share article link

Share