Skip to main content
AAN.com
Brief Communications
June 12, 2001

Local vs systemic corticosteroids in the treatment of carpal tunnel syndrome

June 12, 2001 issue
56 (11) 1565-1567

Abstract

The authors compared the effectiveness of low-dose, short-term oral prednisolone vs local methylprednisolone injection in a prospective, double-blinded, parallel treatment study of carpal tunnel syndrome (CTS). A single injection of 15 mg methylprednisolone resulted in significant improvement in global symptom scores over a 12-week period. This study demonstrated the superiority of local steroid injection to oral steroid in the treatment of CTS.

Get full access to this article

View all available purchase options and get full access to this article.

References

1.
Wood MR. Hydrocortisone injections for carpal tunnel syndrome. Hand . 1980; 12: 62–64.
2.
Ozdogan H, Yazici H. The efficacy of local steroid injections in idiopathic carpal tunnel syndrome: a double-blind study. Br J Rheumatol . 1984; 23: 272–275.
3.
Girlanda P, Dattola R, Venuto C, et al. Local steroid treatment in idiopathic carpal tunnel: short- and long-term efficacy. J Neurol . 1993; 240: 187–190.
4.
Gelberman RH, Aronson D, Weisman MH. Carpal tunnel syndrome: results of a prospective trial of steroid injection and splinting. J Bone Joint Surg Am . 1980; 62: 1181–1184.
5.
Dammers JW, Veering M, Vermeulen M. Injection with methylprednisolone proximal to the carpal tunnel: randomized double blind trial. BMJ . 1999; 319: 884–886.
6.
Chang MH, Chiang HT, SSJ Lee, et al. Oral drug of choice in carpal tunnel syndrome. Neurology 1998;51:390–393.
7.
Herskovitz S, Berger AR, Lipton RB. Low-dose, short-term oral prednisone in the treatment of carpal tunnel syndrome. Neurology . 1995; 45: 1923–1925.
8.
American Academy of Neurology, American Association of Electrodiagnostic Medicine, American Academy of Physical Medicine and Rehabilitation. Practice parameter for electro-diagnostic studies in carpal tunnel syndrome (summary statement). Neurology . 1993; 43: 2404–2405.
9.
Giannini F, Passero S, Cioni R. Electrophysiologic evaluation of local steriod injection in carpal tunnel syndrome. Arch Phys Med Rehabil . 1991; 72: 738–742.
10.
Padua L, Padua R, Lo Monaco M, et al. Multiperspective assessment of carpal tunnel syndrome: a multicenter study. Italian CTS Study Group. Neurology . 1999; 53: 1654–1659.

Information & Authors

Information

Published In

Neurology®
Volume 56Number 11June 12, 2001
Pages: 1565-1567
PubMed: 11402116

Publication History

Received: September 28, 2000
Accepted: January 27, 2001
Published online: June 12, 2001
Published in print: June 12, 2001

Permissions

Request permissions for this article.

Authors

Affiliations & Disclosures

S.M. Wong, MD
From the Department of Medicine and Therapeutics (Drs. S.M. Wong, Hui, K.S. Wong, Kay, and Li, and A. Tang) and Department of Orthopaedics (Drs. Ho and Hung), Prince of Wales Hospital, The Chinese University of Hong Kong, China.
A.C.F. Hui, MD
From the Department of Medicine and Therapeutics (Drs. S.M. Wong, Hui, K.S. Wong, Kay, and Li, and A. Tang) and Department of Orthopaedics (Drs. Ho and Hung), Prince of Wales Hospital, The Chinese University of Hong Kong, China.
A. Tang, BSc
From the Department of Medicine and Therapeutics (Drs. S.M. Wong, Hui, K.S. Wong, Kay, and Li, and A. Tang) and Department of Orthopaedics (Drs. Ho and Hung), Prince of Wales Hospital, The Chinese University of Hong Kong, China.
P.C. Ho, MD
From the Department of Medicine and Therapeutics (Drs. S.M. Wong, Hui, K.S. Wong, Kay, and Li, and A. Tang) and Department of Orthopaedics (Drs. Ho and Hung), Prince of Wales Hospital, The Chinese University of Hong Kong, China.
L.K. Hung, MD
From the Department of Medicine and Therapeutics (Drs. S.M. Wong, Hui, K.S. Wong, Kay, and Li, and A. Tang) and Department of Orthopaedics (Drs. Ho and Hung), Prince of Wales Hospital, The Chinese University of Hong Kong, China.
K.S. Wong, MD
From the Department of Medicine and Therapeutics (Drs. S.M. Wong, Hui, K.S. Wong, Kay, and Li, and A. Tang) and Department of Orthopaedics (Drs. Ho and Hung), Prince of Wales Hospital, The Chinese University of Hong Kong, China.
R. Kay, MD
From the Department of Medicine and Therapeutics (Drs. S.M. Wong, Hui, K.S. Wong, Kay, and Li, and A. Tang) and Department of Orthopaedics (Drs. Ho and Hung), Prince of Wales Hospital, The Chinese University of Hong Kong, China.
E. Li, MD
From the Department of Medicine and Therapeutics (Drs. S.M. Wong, Hui, K.S. Wong, Kay, and Li, and A. Tang) and Department of Orthopaedics (Drs. Ho and Hung), Prince of Wales Hospital, The Chinese University of Hong Kong, China.

Notes

Address correspondence and reprint requests to Dr. SM Wong, Department of Medicine, Prince of Wales Hospital, 30-32 Ngan Shing Street, Shatin, New Territories, Hong Kong, China; e-mail: [email protected]

Metrics & Citations

Metrics

Citation information is sourced from Crossref Cited-by service.

Citations

Download Citations

If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Select your manager software from the list below and click Download.

Cited By
  1. A systematic review of steroid use in peripheral nerve pathologies and treatment, Frontiers in Neurology, 15, (2024).https://doi.org/10.3389/fneur.2024.1434429
    Crossref
  2. Comparison of local versus intramuscular steroid injection in patients with carpal tunnel syndrome: A prospective open label randomized clinical trial, Journal of Clinical Neuroscience, 123, (55-61), (2024).https://doi.org/10.1016/j.jocn.2024.03.023
    Crossref
  3. Bone and Rheumatic Disorders in Diabetes, Textbook of Diabetes, (853-866), (2024).https://doi.org/10.1002/9781119697473.ch59
    Crossref
  4. Usefulness of Ultrasound for Carpal Tunnel Syndrome Proven in Meta-Analysis Studies, Clinical Pain, 22, 1, (9-13), (2023).https://doi.org/10.35827/cp.2023.22.1.9
    Crossref
  5. Methylprednisolone as an Adjunct to Local Infiltration on Laminoplasty or Laminectomy before Wound Closure: A Randomized Controlled Trial, Pain Research and Management, 2022, (1-10), (2022).https://doi.org/10.1155/2022/2274934
    Crossref
  6. Comparison of Distal and Proximal Local Steroid Injection for Carpal Tunnel Syndrome: a Systematic Review and Meta-analysis of Randomized Controlled Trials, Pain and Therapy, 11, 4, (1389-1402), (2022).https://doi.org/10.1007/s40122-022-00444-3
    Crossref
  7. Effect of ultrasound-guided versus landmark-guided local corticosteroid injection for carpal tunnel syndrome: a systematic review and meta-analysis, Archives of Orthopaedic and Trauma Surgery, 143, 1, (545-561), (2022).https://doi.org/10.1007/s00402-022-04437-x
    Crossref
  8. Ultrasound-guided perineural vs. peritendinous corticosteroid injections in carpal tunnel syndrome: a randomized controlled trial, European Journal of Physical and Rehabilitation Medicine, 57, 5, (2021).https://doi.org/10.23736/S1973-9087.21.06682-X
    Crossref
  9. Comparison Between Distal and Proximal Approaches for Local Corticosteroid Injection in Carpal Tunnel Syndrome Management: A Randomized Controlled Trial, HAND, 18, 1_suppl, (48S-55S), (2021).https://doi.org/10.1177/15589447211052759
    Crossref
  10. Ultrasound-guided local corticosteroid injection for carpal tunnel syndrome: A meta-analysis of randomized controlled trials, Clinical Rehabilitation, 35, 11, (1506-1517), (2021).https://doi.org/10.1177/02692155211014702
    Crossref
  11. See more
Loading...

View Options

Login options

Check if you have access through your login credentials or your institution to get full access on this article.

Personal login Institutional Login
Purchase Options

The neurology.org payment platform is currently offline. Our technical team is working as quickly as possible to restore service.

If you need immediate support or to place an order, please call or email customer service:

  • 1-800-638-3030 for U.S. customers - 8:30 - 7 pm ET (M-F)
  • 1-301-223-2300 for customers outside the U.S. - 8:30 - 7 pm ET (M-F)
  • [email protected]

We appreciate your patience during this time and apologize for any inconvenience.

View options

PDF and All Supplements

Download PDF and Supplementary Material

Full Text

View Full Text

Full Text HTML

View Full Text HTML

Media

Figures

Other

Tables

Share

Share

Share article link

Share