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Abstract

Article abstract— The authors reviewed the clinical features and outcome of Miller Fisher syndrome (MFS) for 50 consecutive patients with MFS including 28 patients who received no immunotherapy. Besides the characteristic clinical triad (ophthalmoplegia, ataxia, and areflexia), pupillary abnormalities, blepharoptosis, and facial palsy are frequent in MFS, whereas sensory loss is unusual despite the presence of profound ataxia. Patients with MFS usually had good recovery and no residual deficits.

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References

1.
Fisher CM. An unusual variant of acute idiopathic polyneuritis (syndrome of ophthalmoplegia, ataxia and areflexia). N Engl J Med . 1956; 255: 57–65.
2.
ter Bruggen JP, van der Meché FGA, de Jager AEJ, Polman CH. Ophthalmoplegic and lower cranial nerve variants merge into classical Guillain–Barré syndrome. Muscle Nerve . 1998; 21: 239–242.
3.
Rees JH, Soudain SE, Gregson NA, Hughes RAC. Campylobacter jejuni infection and Guillain–Barré syndrome. N Engl J Med . 1995; 333: 1374–1379.
4.
Hirayama K, Fukutake T, Kawamura M. ‘Thumb localizing test’ for detecting a lesion in the posterior column–medial lemniscal system. J Neurol Sci . 1999; 167: 45–49.
5.
Arnason GBW. Acute inflammatory demyelinating polyneuropathy. In: Dyck PJ, Thomas PK, Griffin JW, Low PA, Poduslo JF, eds. Peripheral neuropathy. 3rd ed. Philadelphia: Saunders, 1993: 1437–1497.
6.
Lyu R-K, Tang L-M, Cheng S-Y, Hsu W-C, Chen S-T. Guillain–Barré syndrome in Taiwan: a clinical study of 167 patients. J Neurol Neurosurg Psychiatry . 1997; 63: 494–500.
7.
Yuki N, Taki T, Takahashi T, Saito K, Yoshino H, Tai T. Molecular mimicry between GQ1b gangliosides and lipopolysaccharides of Campylobacter jejuni isolated from patients with Fisher’s syndrome. Ann Neurol . 1994; 36: 791–793.
8.
Chida K, Takase S, Itoyama Y. Development of facial palsy during immunoadsorption plasmapheresis in Miller Fisher syndrome: a clinical report of two cases. J Neurol Neurosurg Psychiatry . 1998; 64: 399–401.
9.
Kuwabara S, Asahina M, Nakajima M, et al. Special sensory ataxia in Miller Fisher syndrome detected by postural body sway analysis. Ann Neurol . 1999; 45: 533–536.
10.
McKhann GM, Griffin JW, Cornblath DR, Mellits ED, Fisher RS, Quaskey SA, The Guillain–Barré Syndrome Study Group. Plasmapheresis and Guillain–Barré syndrome: analysis of prognostic factors and the effect of plasmapheresis. Ann Neurol . 1988; 23: 347–353.

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Published In

Neurology®
Volume 56Number 8April 24, 2001
Pages: 1104-1106
PubMed: 11320188

Publication History

Received: September 7, 2000
Accepted: January 16, 2001
Published online: April 24, 2001
Published in print: April 24, 2001

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Authors

Affiliations & Disclosures

Masahiro Mori, MD
From the Department of Neurology (Drs. Mori, Kuwabara, Fukutake, and Hattori), Chiba University School of Medicine, Chiba, Japan; and Department of Neurology (Dr. Yuki), Dokkyo University School of Medicine, Tochigi, Japan.
Satoshi Kuwabara, MD
From the Department of Neurology (Drs. Mori, Kuwabara, Fukutake, and Hattori), Chiba University School of Medicine, Chiba, Japan; and Department of Neurology (Dr. Yuki), Dokkyo University School of Medicine, Tochigi, Japan.
Toshio Fukutake, MD
From the Department of Neurology (Drs. Mori, Kuwabara, Fukutake, and Hattori), Chiba University School of Medicine, Chiba, Japan; and Department of Neurology (Dr. Yuki), Dokkyo University School of Medicine, Tochigi, Japan.
Nobuhiro Yuki, MD, PhD
From the Department of Neurology (Drs. Mori, Kuwabara, Fukutake, and Hattori), Chiba University School of Medicine, Chiba, Japan; and Department of Neurology (Dr. Yuki), Dokkyo University School of Medicine, Tochigi, Japan.
Takamichi Hattori, MD
From the Department of Neurology (Drs. Mori, Kuwabara, Fukutake, and Hattori), Chiba University School of Medicine, Chiba, Japan; and Department of Neurology (Dr. Yuki), Dokkyo University School of Medicine, Tochigi, Japan.

Notes

Address correspondence and reprint requests to Dr. Masahiro Mori, Department of Neurology, Chiba University School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670 Japan; e-mail [email protected]

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  1. RELATO DE CASO: ABORDAGEM DO DIAGNÓSTICO CLÍNICO EM UM JOVEM COM SÍNDROME DE MILLER FISHER, REVISTA FOCO, 17, 9, (e6211), (2024).https://doi.org/10.54751/revistafoco.v17n9-122
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  2. Understanding the diagnostic challenges of Miller Fisher syndrome in children: a case report from an ophthalmological perspective, British Journal of Hospital Medicine, 85, 8, (1-5), (2024).https://doi.org/10.12968/hmed.2024.0019
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