Neurology: Clinical Practice Manuscript Classifications

Specifications for Manuscript Categories

Research Articles

Original contributions of direct relevance and importance to clinical practice. We will consider: prospective, observational and retrospective studies, meta-analyses and drug trials.

Research Article	Specification	Details
Word Count	3000 words maximum	Word count does not include Title Page, Acknowledgements, Abstract, References, Figure Legends, Table Legends
Abstract	250 words maximum	Provide Structured Abstract with four subheadings: Background, Methods, Results, Conclusions If applicable, include Classification of Evidence statement (studies of therapeutic interventions or diagnostic accuracy) If applicable, include clinical trial registration number and registry name
Introduction	250 words maximum	Make the Introduction general enough to orient a reader not familiar with the specifics of the field
Methods	Subsection required	Include a Subsection in the Methods titled: "Standard Protocol Approvals, Registrations, and Patient Consents" Include information in this Subsection regarding each of the following: Statement of approval by an ethical standards committee on human experimentation (institutional or regional) for any experiments using human subjects. Statement identifying the institutional or licensing committee approving experiments performed on live vertebrates and/or higher invertebrates. Statement that written informed consent was obtained from all participants (or guardians of participants) in the study (consent for research). For a retrospective analysis that is IRB-approved, state that approval from an ethical standards committee to conduct this study was received. Statement that authorization has been obtained for disclosure (consent-to-disclose) of any recognizable persons in photographs, videos, or other information that may be published in the Journal, in derivative works by the AAN, or on the Journal's Web site (when applicable)
References	40 maximum	If essential, provide additional References as Supplemental File for online only publication
Tables and Figures	Not to exceed 5 total	If essential, provide additional Tables and Figures as Supplemental Files for online only publication
EQUATOR Reporting Guidelines and Checklists	If applicable, provide required checklist as a Supplemental File	CONSORT Statement: Use when reporting the results of Phase 1, Phase 2, or Phase 3 randomized controlled trials PRISMA Statement: Use when reporting systematic review or meta-analysis of randomized trials (previously named QUOROM) STARD Statement: Use when reporting diagnostic accuracy STROBE Statement: Use when reporting case-controlled, cohort, and cross-sectional observational studies and all observational studies of human subjects as well as case series, pilot studies, genetic linkage studies, and retrospective data collection studies STROND Statement: Use when reporting population-based prevalence and incidence studies of neurologic disorders

Review Articles

Comprehensive, scholarly and balanced articles that present an expert examination of literature on a topic. We will consider: systematic reviews, meta-analyses and non-systematic/narrative reviews. Case reports or clinical vignettes used to illustrate a clinical approach or investigations/diagnosis/treatment to a challenging clinical or ethical presentation and accompanied by a comprehensive review of the literature should be submitted as a Review Article. Review Articles should comment on the quality of the available evidence and draw from the author’s practical experience about situations not covered by available evidence. Some Review Articles are invited, but the editors welcome unsolicited submissions and suggestions of topics/authors for consideration.

Review Article	Specification	Details
Word Count	3000 words maximum	Word count does not include Title Page, Acknowledgements, Abstract, References, Figure Legends, Table Legends
Abstract	150 words maximum	Provide Structured Abstract with three subheadings: Purpose of Review, Recent Findings, Summary
Methods	If applicable	Describe in the Methods how information was gathered, selected, and analyzed
References	40 maximum	If essential, provide additional references as a Supplemental File for online only publication
Tables and Figures	Not to exceed 5 total	If essential, provide additional Tables and Figures as Supplemental Files for online only publication
EQUATOR Reporting Guidelines and Checklists	If applicable, provide required checklist as a Supplemental File	PRISMA Statement: Use when reporting systematic review or meta-analysis of randomized trials (previously named QUOROM) STROND Statement: Use when reporting population-based prevalence and incidence studies of neurologic disorders
Additional	Take-home messages	Optional: Provide 3-5 "Take-home points"

Five New Things

Five New Things articles are up-to-date reviews of recent findings in fields such as Parkinson disease, multiple sclerosis, gliomas and stroke.

Five New Things	Specification	Details
Word Count	2000 words maximum	Word count does not include Title Page, Acknowledgements, Abstract, References, Figure Legends, Table Legends
Abstract	150 words maximum	Provide Structured Abstract with three subheadings: Purpose of Review, Recent Findings, Summary
Methods	No	Not applicable
References	25 maximum	If essential, provide additional references as a Supplemental File for online only publication
Tables and Figures	Not to exceed 3 total	If essential, provide additional Tables and Figures as Supplemental Files for online only publication
EQUATOR Reporting Guidelines and Checklists	No	Not applicable
Additional	Take-home messages	Provide 5 bullet points for Five New Things Summary Box

Drugs and Devices

Drugs and Devices articles are reviews of recent advancements and timely issues concerning diagnostic tools and emerging therapies.

Drugs and Devices	Specification	Details
Word Count	2000 words maximum	Word count does not include Title Page, Acknowledgements, Abstract, References, Figure Legends, Table Legends
Abstract	150 words maximum	Provide Structured Abstract with three subheadings: Purpose of Review, Recent Findings, Summary
Methods	No	Not applicable
References	25 maximum	If essential, provide additional references as a Supplemental File for online only publication
Tables and Figures	Not to exceed 3 total	If essential, provide additional Tables and Figures as Supplemental Files for online only publication
EQUATOR Reporting Guidelines and Checklists	No	Not applicable
Additional	Take-home messages	Optional: Provide 3-5 "Take-home points"

Commentaries

Timely analysis of current advances and insights into future directions of recent research findings, health policy issues, or practice management concerns of broad interest to clinical practice (e.g. diagnostic, therapeutic, political, social, ethical, economic, career, etc.) Where possible, authors should strive to make the material relevant to international readers as well as U.S. neurologists. Some Commentaries are invited, but the editors welcome unsolicited submissions and suggestions of topics/authors for consideration.

Commentary	Specification	Details
Word Count	1500 words maximum	Word count does not include Title Page, Acknowledgements, Abstract, References, Figure Legends, Table Legends
Abstract	150 words maximum	Provide Unstructured Abstract
References	25 maximum	If essential, provide additional references as a Supplemental File for online only publication
Tables and Figures	Not to exceed 3 total	If essential, provide additional Tables and Figures as Supplemental Files for online only publication
EQUATOR Reporting Guidelines and Checklists	No	Not applicable
Additional	Conclusion section	Address the following questions in the Conclusion section: What are the unanswered questions? Where is the field going? What are the practical implications?

Case Reports

IMPORTANT: Most Case Reports will be published on-line only. Case Reports published on-line will be listed on the Table of Contents of a print issue.

Case reports should be concise and focus on unique manifestations or new observations of a clinical case. A good case report for practitioners should be unusual and informative to mechanism or educational and narrative. Evidence should be referenced from high quality studies, and discussion should concentrate on the risks and benefits in an individual patient (preferences, particular circumstances). Reports of clinical cases must have a clear message that might influence clinical practice.

Full Case	Specification	Details
Word Count	750 words maximum	Word count does not include Title Page, Acknowledgements, Abstract, References, Figure Legends, Table Legends
Abstract	No	Not applicable
References	7 maximum	If essential, provide additional references as a Supplemental File for online only publication
Tables and Figures	Not to exceed 2 total	If essential, provide additional Tables and Figures as Supplemental Files for online only publication
Additional	Practical Implications Statement	Provide a "Practical Implications" statement after the Title Page -- a pearl of wisdom for the practicing clinician, e.g. "Consider X in the differential diagnosis of Y" or "X imaging may be helpful in distinguishing Y in A patients"

Short Case

Short Case	Specification	Details
Word Count	250 words maximum	Word count does not include Title Page, Acknowledgements, Abstract, References, Figure Legends, Table Legends
Abstract	No	Not applicable
References	2 maximum	If essential, provide additional references as a Supplemental File for online only publication
Tables and Figures	Not to exceed 2 total	If essential, provide additional Tables and Figures as Supplemental Files for online only publication

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